ID B3DZ10_METI4 Unreviewed; 346 AA.
AC B3DZ10;
DT 22-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Naringenin-chalcone synthase {ECO:0000313|EMBL:ACD84102.1};
GN Name=bcsA {ECO:0000313|EMBL:ACD84102.1};
GN OrderedLocusNames=Minf_2048 {ECO:0000313|EMBL:ACD84102.1};
OS Methylacidiphilum infernorum (isolate V4) (Methylokorus infernorum (strain
OS V4)).
OC Bacteria; Verrucomicrobiota; Methylacidiphilae; Methylacidiphilales;
OC Methylacidiphilaceae; Methylacidiphilum (ex Ratnadevi et al. 2023).
OX NCBI_TaxID=481448 {ECO:0000313|EMBL:ACD84102.1, ECO:0000313|Proteomes:UP000009149};
RN [1] {ECO:0000313|EMBL:ACD84102.1, ECO:0000313|Proteomes:UP000009149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate V4 {ECO:0000313|Proteomes:UP000009149};
RX PubMed=18593465; DOI=10.1186/1745-6150-3-26;
RA Hou S., Makarova K.S., Saw J.H., Senin P., Ly B.V., Zhou Z., Ren Y.,
RA Wang J., Galperin M.Y., Omelchenko M.V., Wolf Y.I., Yutin N., Koonin E.V.,
RA Stott M.B., Mountain B.W., Crowe M.A., Smirnova A.V., Dunfield P.F.,
RA Feng L., Wang L., Alam M.;
RT "Complete genome sequence of the extremely acidophilic methanotroph isolate
RT V4, Methylacidiphilum infernorum, a representative of the bacterial phylum
RT Verrucomicrobia.";
RL Biol. Direct 3:26-26(2008).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531}.
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DR EMBL; CP000975; ACD84102.1; -; Genomic_DNA.
DR RefSeq; WP_012464384.1; NC_010794.1.
DR AlphaFoldDB; B3DZ10; -.
DR STRING; 481448.Minf_2048; -.
DR KEGG; min:Minf_2048; -.
DR eggNOG; COG3424; Bacteria.
DR HOGENOM; CLU_034992_0_2_0; -.
DR OrthoDB; 9786288at2; -.
DR Proteomes; UP000009149; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR013601; FAE1_typ3_polyketide_synth.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR PANTHER; PTHR11877:SF46; TYPE III POLYKETIDE SYNTHASE A; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF08392; FAE1_CUT1_RppA; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
FT DOMAIN 28..202
FT /note="FAE"
FT /evidence="ECO:0000259|Pfam:PF08392"
FT DOMAIN 220..318
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 142
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 346 AA; 38586 MW; 8DEEDCF0DB541BFF CRC64;
MFLQSIFSLV PERGYKQSEC WEIFSRSPVA QALREPSLQL VQKILLGNSW IDKRHFAVEP
IEMLFDLPAE SLNRKFEELA PKLASLSLRE ILEMSHLKPS ELDALFVCTC TGYLCPGLSS
HIAERVGLRP DSFLIDIVGH GCGAALPTLR AVKSFLSENP GCYAAAVAVE LSSTAFYVDD
DPGTLVSLCI FADGCCSTLW HSSKRGLGWR FKDFFSLHIP QDREKLRFEN SQGKLRNKLH
RSVPVLAAEA VAGLYRDFIA KGGSPAQRLI VHPGGKEVLI ELQKRFPESR FEESAEILRL
YGNMSSPSVL FAFQKGIESQ PEEKEILLFS FGAGFSCYGC RVSRED
//
