ID B3EPB3_CHLPB Unreviewed; 470 AA.
AC B3EPB3;
DT 22-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Radical SAM domain protein {ECO:0000313|EMBL:ACE05252.1};
GN OrderedLocusNames=Cphamn1_2351 {ECO:0000313|EMBL:ACE05252.1};
OS Chlorobium phaeobacteroides (strain BS1).
OC Bacteria; Chlorobiota; Chlorobiia; Chlorobiales; Chlorobiaceae;
OC Chlorobium/Pelodictyon group; Chlorobium.
OX NCBI_TaxID=331678 {ECO:0000313|EMBL:ACE05252.1};
RN [1] {ECO:0000313|EMBL:ACE05252.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BS1 {ECO:0000313|EMBL:ACE05252.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Ovchinnikova G., Li T., Liu Z., Zhao F.,
RA Overmann J., Bryant D.A., Richardson P.;
RT "Complete sequence of Chlorobium phaeobacteroides BS1.";
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CP001101; ACE05252.1; -; Genomic_DNA.
DR AlphaFoldDB; B3EPB3; -.
DR STRING; 331678.Cphamn1_2351; -.
DR KEGG; cpb:Cphamn1_2351; -.
DR eggNOG; COG1032; Bacteria.
DR HOGENOM; CLU_021572_5_1_10; -.
DR OrthoDB; 9801424at2; -.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR PANTHER; PTHR43409:SF12; BLL1977 PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485}.
FT DOMAIN 63..159
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 183..407
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 470 AA; 53060 MW; E1512368684099E4 CRC64;
MSSEKKVLLV FLAADSGVDG AKSLFEEESK KGVKHWFDQS FRSLIKKTQF AIPPLALMIL
ASVDVEGIEQ RICDLRFEEL PLEEPWDLIG ISVQTGMTAK AFNLADTLRS KGFKVALGGA
HVTLFPDSCR QHADVLVHGE ADDIWADVLE DLKNAALQKD YFPVDFPDLS RSRPIASRLL
DKRRYFTTNI IQTGRGCPYS CDFCTVHVLN GNRHRRRSIN DVVDEVIRFS EHDNRIFFFV
DDSINASEDY ALELFERLVP LNITWFGQAT TTLGKQPRLL ETFARSGCQA LLVGIESIEP
ASRERHKKTQ NRSSELAEAI INIRKAGISL YGSFIYGLDG DTLETPAAIL DFIRLTKLDV
PGINILRPNP GTGVFDRLRE EGRLLFDPDD LGAYRYTFGQ EMLYRPKQIS LPDFIESYSQ
LTSEIFTVTG SLRRGLAAPS AKAAVLLFNL FYTHLYSLSR NDLKQQTKRF
//
