ID B3FA97_9CARA Unreviewed; 709 AA.
AC B3FA97;
DT 22-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=CADr {ECO:0000313|EMBL:ABR23810.1};
DE Flags: Fragment;
OS Bembidion californicum.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Adephaga; Caraboidea; Carabidae;
OC Trechinae; Bembidiini; Bembidion; Hirmoplataphus subgenus complex;
OC Hydriomicrus.
OX NCBI_TaxID=447295 {ECO:0000313|EMBL:ABR23810.1};
RN [1] {ECO:0000313|EMBL:ABR23810.1}
RP NUCLEOTIDE SEQUENCE.
RA Maddison D.R.;
RT "Systematics of the North American beetle subgenus Pseudoperyphus
RT (Coleoptera: Carabidae: Bembidion) based upon morphological, chromosomal,
RT and molecular data.";
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 ATP + hydrogencarbonate + NH4(+) = 2 ADP + carbamoyl
CC phosphate + 2 H(+) + phosphate; Xref=Rhea:RHEA:18029,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:17544, ChEBI:CHEBI:28938,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:58228,
CC ChEBI:CHEBI:456216; EC=6.3.4.16;
CC Evidence={ECO:0000256|ARBA:ARBA00043687};
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00605}.
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DR EMBL; EF649386; ABR23810.1; -; Genomic_DNA.
DR AlphaFoldDB; B3FA97; -.
DR MEROPS; C26.956; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016879; F:ligase activity, forming carbon-nitrogen bonds; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.20; -; 2.
DR Gene3D; 3.40.50.880; -; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR Gene3D; 1.10.1030.10; Carbamoyl-phosphate synthetase, large subunit oligomerisation domain; 1.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR005480; CarbamoylP_synth_lsu_oligo.
DR InterPro; IPR036897; CarbamoylP_synth_lsu_oligo_sf.
DR InterPro; IPR005479; CbamoylP_synth_lsu-like_ATP-bd.
DR InterPro; IPR005483; CbamoylP_synth_lsu_CPSase_dom.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR017926; GATASE.
DR InterPro; IPR016185; PreATP-grasp_dom_sf.
DR PANTHER; PTHR11405:SF5; CAD PROTEIN; 1.
DR PANTHER; PTHR11405; CARBAMOYLTRANSFERASE FAMILY MEMBER; 1.
DR Pfam; PF02786; CPSase_L_D2; 1.
DR Pfam; PF02787; CPSase_L_D3; 1.
DR Pfam; PF00117; GATase; 1.
DR PRINTS; PR00098; CPSASE.
DR SMART; SM01096; CPSase_L_D3; 1.
DR SUPFAM; SSF48108; Carbamoyl phosphate synthetase, large subunit connection domain; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF52440; PreATP-grasp domain; 2.
DR PROSITE; PS50975; ATP_GRASP; 1.
DR PROSITE; PS00867; CPSASE_2; 1.
DR PROSITE; PS51273; GATASE_TYPE_1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Pyrimidine biosynthesis {ECO:0000256|ARBA:ARBA00022975}.
FT DOMAIN 225..417
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABR23810.1"
FT NON_TER 709
FT /evidence="ECO:0000313|EMBL:ABR23810.1"
SQ SEQUENCE 709 AA; 78868 MW; DC6B76E5EBC2BB43 CRC64;
TSQNHGFAVD SKTLPTGWKA LFTNANDNTN EGIIHESLPY FSVQFHPEHT AGPQDLECLF
DVFIEAVNSY SPANAINVQE LITRKLTYVP KVPYDMKIPK KVLIIGSGGL SIGQAGEFDY
SGSQAIKALH EENIQTVLIN PNIATVQTSK GLADKVYFLP LVPEYVEQVI RAERPGGVLL
TFGGQTGLNC GVELQRAGVF QKYGVRILGT PIDAIIDTED RKIFADRISV IGEKVAPSCA
VYSVPEAVEA AEKLGYPVMA RAAFSLGGLG SGFADNKEEL KTLALQALAH SSQLIIDKSL
KGWKEVEYEV VRDAYDNCIT VCNMENVDPL GIHTGESIVV APSQTLSNRE YNLLRTTAIN
VIRHFGVVGE CNIQYAVNPY AEEYYIIEVN ARLSRSSALA SKATGYPLAY VAAKLALGIP
LSKIKNSVTG QTTACFEPSL DYCVVKIPRW DLSKFSRVST KIGSSMKSVG EVMAIGRKFE
EAFQKALRMV DENVTGFDPY LRKVDDEELK EPTDKRMFVV AAALKEGYTV DKLYELTKID
RWFLQKMKHI IDYQTLLEKK DQHSLTYTDL LRAKQIGFSD KQIAASVKST ELAIRKQREE
CGVLPFVKQI DTVAAEWPAT TNYLYITYNA SSHDLEFKEE HTMVLGSGVY RIGSSVEFDW
CAVGCLRELR KLGRKTIMVN YNPETVSTDY DMSDRLYFEE ISFEVVMDI
//
