ID B3H0M6_ACTP7 Unreviewed; 933 AA.
AC B3H0M6;
DT 22-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Autotransporter serine protease {ECO:0000313|EMBL:ACE61038.1};
GN Name=aasP {ECO:0000313|EMBL:ACE61038.1};
GN OrderedLocusNames=APP7_0386 {ECO:0000313|EMBL:ACE61038.1};
OS Actinobacillus pleuropneumoniae serotype 7 (strain AP76).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Actinobacillus.
OX NCBI_TaxID=537457 {ECO:0000313|EMBL:ACE61038.1, ECO:0000313|Proteomes:UP000001226};
RN [1] {ECO:0000313|Proteomes:UP000001226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AP76 {ECO:0000313|Proteomes:UP000001226};
RA Linke B., Buettner F., Martinez-Arias R., Goesmann A., Baltes N.,
RA Tegetmeyer H., Singh M., Gerlach G.F.;
RT "Genome and proteome analysis of A. pleuropneumoniae serotype 7.";
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001091; ACE61038.1; -; Genomic_DNA.
DR RefSeq; WP_012478343.1; NC_010939.1.
DR AlphaFoldDB; B3H0M6; -.
DR MEROPS; S08.144; -.
DR KEGG; apa:APP7_0386; -.
DR HOGENOM; CLU_313487_0_0_6; -.
DR Proteomes; UP000001226; Chromosome.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd04848; Peptidases_S8_Autotransporter_serine_protease_like; 1.
DR Gene3D; 2.40.128.130; Autotransporter beta-domain; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR005546; Autotransporte_beta.
DR InterPro; IPR036709; Autotransporte_beta_dom_sf.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034061; Peptidases_S8_Autotransporter.
DR PANTHER; PTHR43399; SUBTILISIN-RELATED; 1.
DR PANTHER; PTHR43399:SF4; TK-SUBTILISIN; 1.
DR Pfam; PF03797; Autotransporter; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SMART; SM00869; Autotransporter; 1.
DR SUPFAM; SSF103515; Autotransporter; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51208; AUTOTRANSPORTER; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..933
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002789198"
FT DOMAIN 672..933
FT /note="Autotransporter"
FT /evidence="ECO:0000259|PROSITE:PS51208"
FT ACT_SITE 58
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 116
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 352
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 933 AA; 103826 MW; B4C601AE6DE4CA56 CRC64;
MLEKYYFNKS CIAIAISTFL STSVAYADSL ESPHSSIKLS DEISAKYSGK GVKLGVLDGG
FVVKHPLHSS KLNLSGFKLT SPDGKPLNYD PGYLQFEVKP VEQNGKKGLA ALFEIHGLAV
SGIISAKASE KEGFKGGVAK EAEIHIATNT PNRSLSELIA EANQSKGEDE EKGDSENQKP
DFNELAKSDL LISKDKKLSF ERLEWATALN KLVERNLFAI NNSWNLDPIS DNIADFDKFY
HSLSTDKQNS LLQAVLNAKK KNTLLVFAAG NESKKQVGVM AMLPRYLPEL EKHYLSVVAV
DNKHNLTDYS NHCGVSKNWC VAAPGNLAIL NAIPDSTTLK PQYNLGKEQG TSLAAPVVTG
ALAILKERFS YLAPTQIRDT LLTTATDLGE KGVDDKYGWG VINIAKAING PSQFLNDETV
NVTRDDRWKN DFSSKFKFTK QGEKSLDLAG KNNIARIDVE QGRLNLSGMT QSQQVKNNAH
LGVNQTEIRQ GYMATENSQL TLLDSNGLIG KDKAIIQLNG SLKIADKLTE NSKQGSISAT
VVKLHDKASY QGGFTKLIDN KNLANKGLMQ DLYFKQSEII AKVNSNKAFT DPNANDNAKS
GLNLLNQLRT SSFAYRQGVY NDWLQSALEK KKLGQLHYAV SNHIYADALA LLRHQNAKQL
SHVQHNLFTA AYSPQKTSVW LEHSGQKHSK VAIKQNSSAL SLSHKFNDNA LLSATLMRKN
HHMDKDFAHA DLKQTSLNIG LRYPLADHWF SELALQFGQQ KYNQRRWYKK SQLGQAQNKG
HHMGGEIRVG YQFMPQTWII EPSLGVQFIQ TRMKALNEKG ELATNTTALH YNDINLTPSV
KLKYTVKFEQ GSISPYVGLN YLHRVKGKES KITSQLNGYP LQSYATQKRN HALNLEAGMQ
FQYKNWFVYA NVDYDRIKST NAFGWKTNIG LTF
//
