ID B3LG45_YEAS1 Unreviewed; 612 AA.
AC B3LG45;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Peroxisomal targeting signal receptor {ECO:0000256|ARBA:ARBA00014710};
DE AltName: Full=Peroxin-5 {ECO:0000256|ARBA:ARBA00032505};
GN ORFNames=SCRG_00282 {ECO:0000313|EMBL:EDV08074.1};
OS Saccharomyces cerevisiae (strain RM11-1a) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=285006 {ECO:0000313|EMBL:EDV08074.1, ECO:0000313|Proteomes:UP000008335};
RN [1] {ECO:0000313|Proteomes:UP000008335}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RM11-1a {ECO:0000313|Proteomes:UP000008335};
RG The Broad Institute Genome Sequencing Platform;
RA Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Cuomo C.,
RA Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M.,
RA Mauceli E.W., Brockman W., MacCallum I.A., Rounsley S., Young S.K.,
RA LaButti K., Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA O'Leary S., Kodira C.D., Zeng Q., Yandava C., Alvarado L., Pratt S.,
RA Kruglyak L.;
RT "Annotation of the Saccharomyces cerevisiae RM11-1a genome.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Interacts (via WxxxF/Y and LVxEF motifs) with PEX14; promoting
CC translocation through the PEX13-PEX14 docking complex.
CC {ECO:0000256|ARBA:ARBA00038659}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}. Peroxisome matrix
CC {ECO:0000256|ARBA:ARBA00004253}.
CC -!- SIMILARITY: Belongs to the peroxisomal targeting signal receptor
CC family. {ECO:0000256|ARBA:ARBA00005348}.
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DR EMBL; CH408043; EDV08074.1; -; Genomic_DNA.
DR AlphaFoldDB; B3LG45; -.
DR HOGENOM; CLU_013516_3_0_1; -.
DR Proteomes; UP000008335; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0005782; C:peroxisomal matrix; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR024111; PEX5/PEX5L.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR10130:SF0; GH08708P; 1.
DR PANTHER; PTHR10130; PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5; 1.
DR Pfam; PF00515; TPR_1; 1.
DR Pfam; PF13432; TPR_16; 1.
DR SMART; SM00028; TPR; 4.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 3.
PE 3: Inferred from homology;
KW Peroxisome {ECO:0000256|ARBA:ARBA00023140};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Thioester bond {ECO:0000256|ARBA:ARBA00022966};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}; Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transport {ECO:0000256|ARBA:ARBA00022448};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT REPEAT 347..380
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 457..490
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 491..524
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 129..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 182..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..47
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 612 AA; 69423 MW; 188140982AD71A13 CRC64;
MDVGSCSVRN NPLAQLHKHT QQNKSLQFNQ KNNGRLNESP LQGTNKPGIS EAFISNVNAI
SQENMANMQR FINGEPLIDD KRRMEIGPSS GRLPPFSNVH SLQTSANPTQ IKGVNDISHW
SQEFQGSNSI QNRNADTGNS EKAWQRGSTT ASSRFQYPNT MMNNYAYASM NSLSGSRLQS
PAFMNQQQSG RSKEGVNEQE QQPWTDQFEK LEKEVSENLD INDEIEKEEN VSEVEQNKPE
TVEKEEGVYG DQYQSDFQEV WDSIHKDAEE VLPSELVNDD LNLGEDYLKY LGGRVNGNIE
YAFQSNNEYF NNPNAYKIGC LLMENGAKLS EAALAFEAAV KEKPDHVDAW LRLGLVQTQN
EKELNGISAL EECLKLDPKN LEAMKTLAIS YINEGYDMSA FTMLDKWAET KYPEIWSRIK
QQDDKFQKEK GFTHIDMNAH ITKQFLQLAN NLSTIDPEIQ LCLGLLFYTK DDFDKTIDCF
ESALRVNPND ELMWNRLGAS LANSNRSEEA IQAYHRALQL KPSFVRARYN LAVSSMNIGC
FKEAAGYLLS VLSMHEVNTN NKKGDVGSLL NTYNDTVIET LKRVFIAMNR DDLLQEVKPG
MDLKRFKGEF SF
//
