ID B3M4W7_DROAN Unreviewed; 2715 AA.
AC B3M4W7;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 2.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Uncharacterized protein, isoform D {ECO:0000313|EMBL:EDV40541.2};
GN Name=Dana\GF10562 {ECO:0000313|EMBL:EDV40541.2};
GN Synonyms=dana_GLEANR_10516 {ECO:0000313|EMBL:EDV40541.2};
GN ORFNames=GF10562 {ECO:0000313|EMBL:EDV40541.2};
OS Drosophila ananassae (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7217 {ECO:0000313|EMBL:EDV40541.2, ECO:0000313|Proteomes:UP000007801};
RN [1] {ECO:0000313|EMBL:EDV40541.2, ECO:0000313|Proteomes:UP000007801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 14024-0371.13 {ECO:0000313|Proteomes:UP000007801};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CH902618; EDV40541.2; -; Genomic_DNA.
DR RefSeq; XP_001957735.2; XM_001957699.2.
DR SMR; B3M4W7; -.
DR EnsemblMetazoa; FBtr0391817; FBpp0351240; FBgn0087603.
DR GeneID; 6493431; -.
DR KEGG; dan:6493431; -.
DR eggNOG; KOG1787; Eukaryota.
DR HOGENOM; CLU_002876_0_0_1; -.
DR OrthoDB; 47483at2759; -.
DR Proteomes; UP000007801; Unassembled WGS sequence.
DR CDD; cd06071; Beach; 1.
DR CDD; cd01201; PH_BEACH; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR046851; NBCH_WD40.
DR InterPro; IPR031570; NBEA/BDCP_DUF4704.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13743:SF112; BEACH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13743; BEIGE/BEACH-RELATED; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF15787; DUF4704; 1.
DR Pfam; PF16057; DUF4800; 1.
DR Pfam; PF20426; NBCH_WD40; 1.
DR Pfam; PF14844; PH_BEACH; 1.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007801};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 1909..2006
FT /note="BEACH-type PH"
FT /evidence="ECO:0000259|PROSITE:PS51783"
FT DOMAIN 2019..2311
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REPEAT 2461..2496
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 2539..2580
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1405..1442
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2715 AA; 305139 MW; 82216A48E1B5B717 CRC64;
MDNKKDIYNL WVQYTTKNDE SYFREFVARF VAIWRSQLQL DFQAENCPLW NEVKTDSGPH
LGRLPDELLP AIGKFIIVAR DECDTAGHLD EEAIEQVAIL IDCLVIVCRH FDNILAIIKY
EYKPNLIAIL TRVFKQQMSE TQTTAATSHL FRSFSAFLEV MYDPYLTWRS FVRGHSADYS
RLSYKPHSVH VEIVPFIYDC FQEEKLIRYA EIGESLLNIL GAVICGSQRN GMKAICPATV
SITMGILRQW ESTNSLRCVA LNCYALMVIV LQKSSPEERQ IDLVTLVQLY CDALQELLAT
KHFESGDANF DIASDADQDV AIDMSALSST VAAVKLFLGR DSAACEAIVE TNLLEILTNL
PKLIQPWHIS HSSSLCSTME ALATLTRNSP QSANQLRQAE RIEKLFVSLR NFGSPTVSLL
DSCFMLGYDD QKHLLLLPEV MLELLNWVPV LQEQEQLHVT NLVLKGCTDN YGTKSVACGS
HVIKAVCGCL LKAESLGENC VQNLIKLIEE LSKLSIVPVE LKCIFALLRQ GTKFPQNKQL
QQTLVVIALQ SLRGSNSCSQ YFAIEQQTDG IAVPDIRNWT ISGSYGFIFH ILVRFNQLKD
QPSNRRMLLT LQTASGSGFE VFVQPNGNVV VAALTRREYL TSSTATKTLM DGQWHYLTVA
ITPPKRPFSY SQINIYVDFV QKLSATLKVQ AVNEPFTVCS IGAVVAPPQP GEVAKSGIMP
RSSSQESGSS GYKGMLPSLL ERTLSANVSN YFTLPMRTQT AFDPNVKNFP IGMQDTVFGE
QTCLNGHLGG VLLAEPTTNL KTIFDAGANF SSIFSQDNDL LELNSRFVFC YAPGAIWHGV
CQDLIPGGKY PGRISARHCK IVKIQETINS IGGISAILPI LHRLVSSDQA ADISIASVSE
DSNASCVPTP TAEEFTDWEM LSSNSYTEWK MLQHPVASFL CLLRYLTHEH EMNQEQLLAS
ECLAIVGTML QRCPPALFDV NALMATHLLM ESLQGHKSEA GGQLLDALYA HIVFDFAIWS
RLQFQITLGH VQYLSAMIKN DRKFFRRRYG VQFVLDVVRQ YYSTPDSISD EDAKTIRATL
FGIIRFYLQK DVNIKEVNAM VAFLASVRQD VVLVEFLEMM TLYLRGKNCK DQMVLLLHEP
QSANLIYNFF VDKSYNNQIQ EAAIRFISGL LATSRVHQKY KQVLRLYDQV TEQSMFPGFF
SFITPLSLSS TILFHLVDEM LGLQPDYAGL IFLVYHVSSC DLPVKLEIAK RLLQTTFVKQ
NSTVAMAKQT GWQESIARLL IRKPITSSPP DEEKRRSFGI NMDVLLEDNS TFLAQADLIT
FSDQEIGLAQ LQQQQEEEEQ SDSGLILNEI QASVSEAATV IESEIKELAE SVSGAVVENA
SSLFSVIRQT THDIQDTFES LTLGSSIDTT DGSQTPSIQR EESLSSDSST QSPHGAPKKS
DSLESTSAFD FVADGDVDTE EQLVYLVSNT LFNIFWRGIS NDHPHCWQER GQVLGCINLL
ALNNELITSH LSLRLRILEM AVQASLFDLS EHGSQTLVNQ ENASHILRMV YELVVLGSNE
DESKKCSTKL LDGVLALLDA LMIFQQGSSD DWSDMIRLCL GLLLKCSHHP NPGIVAMATA
KLHAILQSRS TEDPAELSYL LYSINRALDN AIEVGNPEEY SFLMPVMKAL LEKCRLAFNL
ESTLPDLPST SAGPVFFNDF QMYSTSKKWR NFIDRMIKPL YDRYQRDIEL HLWEPINRFW
AECYEACKAA SKQRATHQAE NRRLFQQKIY MPWKVRQVEE MQRLQAAALH HKTIDSHIRK
RWKTAKRFLY GPRGPWYTGD LDEEFWKLSP HENVARMRLK LEPQLYPNKH ENAANLRDNA
TSAYDTKEIS EFDSTIKNAV VRDFLADDES SQLEEELKQL IDSQAQQDVA LEKLVISQDC
ELITLMTKVK GRIEVNQSIF TFVDLSPPTE DGSKHDFRFS TNKIREVHLR KYNLRRSALE
IFLVDQTSYF LNFTTKTRNK VFTKIVGLPL PNILYGSGRS PAELLRASGL TQRWINREIS
NFEYLMYLNT IAGRSYNDLS QYPVFPWILA DYTSDVLDLT DPKSFRDLSK PIGCINPKNE
AEVRSKYDSF EDPSGAIPKF HYGTHYSNSA GVLHYLLRVE PFTSLHIDLQ SGRFDVADRQ
FHSIPQTWKL LMDNPNDVKE LIPEFFYFPE FLKNMNKFDL GHLQITKEKV DDVILPAWAT
TPEEFIAIHR RALESEYVSQ HLHHWIDLIF GYKQKGPKAA EALNVFYYCS YEGAVDLDKI
TNPVEREAVE GMINNFGQVP SQLLREPHPR RLTQDETCLK LVRAELRRPD LTQFLDKVVQ
YYCELSTPKD PIVYLSPPRS PPRSFLQLSP DVLVSVSKSS ILGCNSWLSF DKDQGFLLEI
DATTANLKNR KRVFGPFHPS QPPHSQLFAV STDGKLLYAG GIWDNSLRVY NVNKGKALAS
VTRHLDIITC IALDNCGSYL VTGSRDCTCI VWSIQSNHQG GGPSTSNIPV HALTGQSHLQ
AITQLNTQNS YSPKPLTVLH GHDDAISSVA IYTELDLVVS GSLDGTVNVY TLQEGQFVRT
LKPIGCTESC VQISFVTVSY HGHIAFSALD DTSHSVHVYS INGCSLGSKY VSGRVTGLAS
ASDYLVVADD AGDITMSRLH GLKPIFDIPL HVPIQTVVVT PGNTHILAPL RDGRLAVIAV
QLPSGVNKKH SVLNV
//
