ID B3RML6_TRIAD Unreviewed; 1658 AA.
AC B3RML6;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE RecName: Full=ABC transporter domain-containing protein {ECO:0000259|PROSITE:PS50893};
GN ORFNames=TRIADDRAFT_49936 {ECO:0000313|EMBL:EDV28384.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV28384.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV28384.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV28384.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS985242; EDV28384.1; -; Genomic_DNA.
DR RefSeq; XP_002110218.1; XM_002110182.1.
DR EnsemblMetazoa; TriadT49936; TriadP49936; TriadG49936.
DR GeneID; 6751433; -.
DR KEGG; tad:TRIADDRAFT_49936; -.
DR CTD; 6751433; -.
DR eggNOG; KOG0059; Eukaryota.
DR HOGENOM; CLU_000604_19_1_1; -.
DR InParanoid; B3RML6; -.
DR OMA; WKNWIVL; -.
DR OrthoDB; 5486627at2759; -.
DR PhylomeDB; B3RML6; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0005319; F:lipid transporter activity; IBA:GO_Central.
DR GO; GO:0006869; P:lipid transport; IBA:GO_Central.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF250; ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 3; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000009022};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 249..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 893..913
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1082..1102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1123..1149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1161..1185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1192..1213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1285..1306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 526..765
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1324..1557
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1658 AA; 186741 MW; D6C94314041AD0E1 CRC64;
MAKGRQFLLL LWKNFTLLRR SWLTVLFEVF LTVLFVIVLL LVRTDGDLKG KMVPVYEPRS
FTIHSLPSEL VLEHNGKYMA FCPNTSAAVV GVMKRAQRLL DGLQRVDGFA NEEDMVNFLI
SKETQLGQSF SPYIGGVVFH VNGSQFDSQI NYSIRLDYIP RHDAQDASLI GASQTWETKY
TFPIFQIKGP RERHDTTGGS PGYYREGFLA LQWAIDRAII AHLYDLAEPP SVDLEMQRFP
YPSYLDDKFI YIIQNVFPLL LMMSMVVTAL SIVKSVVFEK ERKLKESMKI MGLSNWLHWL
SWFVQYFVFF LISMGIITFF LCTNITSNGR ILDNTNPIVL YLFLMVYSCT SIMWCFLVSV
FFYRSNIAAA AGGILWFLNY VPFFFITFYY SSYSINQKLG ASLLSNVGMA LGATVIGKLE
GQGVGAQWSN FFHPVSVDDS LSLASIVGML LLDAFIYGLL AFYIEAIFPG EFGVPQQWYF
PFTRSYWFGV TPIEFDEERI RLLSNSPSIS QYSHFEKEPT DLQPGISVRN IFKVFNRNKY
CGKSSEEKVA VNDVSVNMYS GQITVLLGHN GAGKTSLMSM LCGMFPPTTG SALVNGHDIC
CDIDRVRNSL GLCPQHDILF DTLTVEEHLR FFAKLKGCPK DRINAEIDRI IEAVGLGDKK
YTFSSSLSGG MKRKLSVGIA LIGDSKVVLL DEPTSGMDPS ARRFTWDLLQ REKANRTILL
TTHFMDEADL LGDRIAIMGK GKVICCGSSL FLKKKYGIGY HMTIVKSATC KVNEIIERVT
KSIDGATLEN NVGSELSFIL PSSGSNKFEL LFCELEEHQT ELGISSFGAS VTTMEEVFLK
VNDIVEKYYS HQGEEERFSQ DSNDCGREDY KLWYQQFCAM LTKRMLHSKR YKWSIISQLL
VPIIFTMIAL IVIKTIPYNG GSPPLSLVTD QFGKNYAPFA YDDNPNTLAY RLSEAYSNQF
NDTSTYPVNI MRFNGTMNGN MTKFALEKSM QDIGAFNSRY MIGAEFHNVK SQSDRVAIKL
WFNNQAFHSI GVTVNYLTNC ILAYGFNTTN ERYTITTTNY PLPPSGSETL TNIKKYALGF
NIAFNLMFGM SFLASSFVIF LIKERSSKAK HVQFVSGVDP LCFWLSSFVW DLFNYMIPCL
ALLVVFAAFD TQAYVDDNRL GIVILILFLY GWAIIPLMYL FSFLFVNSAT GFVVTTMFNI
ITGLVTLITV NIFSIPQLNQ MATANGLKWG FLVLPNYCLG QSLSDMFVNY ITITTCMKNE
LTKLGCKALK VKYQTNYLSW EDPGIGRFAV FMAIEGVVLL VILFLLEYGI LGRIYDSLIC
SGKGQDESVD EEEDVDVNEA TVNNLSIGIS LGECFGLLGV NGAGKTTTFK MLTGDESITS
GTAVMSGFNI KTQLRQARQQ MGYCPQFDAL IELMTGRELL SMFARLRGVP ESRLRQVVEK
IISQLSLKEY ADRLCGTYSG GNKRKLCTGI ALVGNPPVIF LDEPTTGMDP VARRFLWNVL
SKIRAENRCI VITSHSMEEC EALCTRLAIM VNGKFKCLGS PQHLKSKFGQ GYTVIAKVGR
DKPNSIHDQE QIMNRLQAYI EENFPNAVIK DQHHGLIHYY VSDARVSWAK VFSIMEEAKR
TFNLEDYSVG QTTLEDVFLN FAGTQRQQMP PLDDAPIA
//
