ID B3S072_TRIAD Unreviewed; 569 AA.
AC B3S072;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Solute carrier family 23 member 2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=TRIADDRAFT_26431 {ECO:0000313|EMBL:EDV23956.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV23956.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV23956.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV23956.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; DS985246; EDV23956.1; -; Genomic_DNA.
DR RefSeq; XP_002113482.1; XM_002113446.1.
DR AlphaFoldDB; B3S072; -.
DR STRING; 10228.B3S072; -.
DR EnsemblMetazoa; TriadT26431; TriadP26431; TriadG26431.
DR GeneID; 6754694; -.
DR KEGG; tad:TRIADDRAFT_26431; -.
DR CTD; 6754694; -.
DR eggNOG; KOG1292; Eukaryota.
DR HOGENOM; CLU_017959_5_4_1; -.
DR InParanoid; B3S072; -.
DR OMA; GLGFDWN; -.
DR OrthoDB; 911690at2759; -.
DR PhylomeDB; B3S072; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; NF037981; NCS2_1; 1.
DR PANTHER; PTHR11119:SF3; LD30822P; 1.
DR PANTHER; PTHR11119; XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009022};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 221..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EDV23956.1"
SQ SEQUENCE 569 AA; 62107 MW; 31C7D92B0D1837F7 CRC64;
VIYELHEVPP FLYTIGLGLQ HYLTMFGATI SLPFVLAAPL CIGNNNPLAI SDLISTIFFV
SGIATLLQAT FGIRLPIVQG GSFAFVAPIV AIMALDKWKD TCNLTLAQQR NQTEMWQSRI
REIQGGIMLS SLFQIIIGFS GIIGLCLRFI GPITIAPTIT LVGLTLIDAA TFYSSSHWGM
ALLTIFFIAL FSQVLERFPV PMPAFKRGKG CYVTRVHIFR LFPVLIAIIV SWIVSAILTA
AGAFPSDRTN PTYFARTDAR ISVLETSPWF RFPYPFQWGT PTISVASVFG MLAGVLASMI
ESIGDYYACA RLAGAKPPPT HAINRGIGME GIGCVLAGMI GTGSGTTSYS ENIGAIGITR
VASRAVIQCG AVIMIILAII SKFGALFASI PNPVVGGVFI VMFGLVTAVG ISNLQFCNMN
LPRNIFIVGL SLIFGMAFPT WLRTGTNSSV IKTTVKELDQ IIVVLLSTNI AIGGLVALIL
DNVIPGTLED RGMHIWHQES SKASNQMSNE YVKEMKRTYD LPFGLSNFFH KFTCTKYLPF
CPPRYDDLTD ESEQYLDPET GKEYLSYRL
//
