ID B3S354_TRIAD Unreviewed; 466 AA.
AC B3S354;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 24-JAN-2024, entry version 62.
DE RecName: Full=RRM domain-containing protein {ECO:0000259|PROSITE:PS50102};
GN ORFNames=TRIADDRAFT_58601 {ECO:0000313|EMBL:EDV22730.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV22730.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV22730.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV22730.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DS985248; EDV22730.1; -; Genomic_DNA.
DR RefSeq; XP_002114596.1; XM_002114560.1.
DR AlphaFoldDB; B3S354; -.
DR STRING; 10228.B3S354; -.
DR EnsemblMetazoa; TriadT58601; TriadP58601; TriadG58601.
DR GeneID; 6755989; -.
DR KEGG; tad:TRIADDRAFT_58601; -.
DR CTD; 6755989; -.
DR eggNOG; KOG4206; Eukaryota.
DR HOGENOM; CLU_039888_2_1_1; -.
DR InParanoid; B3S354; -.
DR OMA; CPFGPIT; -.
DR OrthoDB; 1331467at2759; -.
DR PhylomeDB; B3S354; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0005689; C:U12-type spliceosomal complex; IBA:GO_Central.
DR GO; GO:0097157; F:pre-mRNA intronic binding; IBA:GO_Central.
DR GO; GO:0030626; F:U12 snRNA binding; IBA:GO_Central.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR CDD; cd12238; RRM1_RBM40_like; 1.
DR CDD; cd12239; RRM2_RBM40_like; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR034147; RBM40_RRM1.
DR InterPro; IPR045164; RBM41/RNPC3.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR16105:SF0; RRM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR16105; UNCHARACTERIZED; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000009022};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 4..80
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 378..461
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 86..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 198..243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..108
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..243
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 466 AA; 52539 MW; 789EC59834EE9F2A CRC64;
MTNCELLIRY LPSIASASDI KELLSNFGAT HVHYFGQHGK MKNCAIAKFD NENTAKQALQ
RLHQLQIFDQ RLVAVYTTEK ARSNIKSSKE SVSDLDSDDD KHSNTKSSRN SKTQDLSKSL
PPVAANLGLN YPSPPDLHYL YPEANIMILT NIVNAMLAVP KFYTQVLHLM NRMNLPPPFA
FPTPTPPMKS KLNQAVANQK EKNSLPISSE ESEIESEDNE SLATNVTSRK RSRTGSKPAN
FSKQLKLPKI NQATVLPASN NKSYDEQYKV LSTVDEVFEN FDKEKRSITE FSLQDAIQNA
YNRNLGEKLE LAGTLASESG AGFGTFAPIV PITEYTSNVE DDMNDSIRLE DLRANRMSKI
ELQKLSVYQN YERKEPTGRL YIKNLSDKVK ESDLIYIYSR FINKDDNSHL DRFDVRLLTR
GRMKGQAFVN LPDEVVATEA VNETHGYVLH GKPMIVDFAQ SAKKKD
//
