ID B3SB89_TRIAD Unreviewed; 209 AA.
AC B3SB89;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU364016};
DE EC=2.4.1.- {ECO:0000256|RuleBase:RU364016};
GN ORFNames=TRIADDRAFT_32618 {ECO:0000313|EMBL:EDV20124.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV20124.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV20124.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV20124.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus, Golgi stack membrane
CC {ECO:0000256|RuleBase:RU364016}; Single-pass type II membrane protein
CC {ECO:0000256|RuleBase:RU364016}. Membrane
CC {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the chondroitin N-
CC acetylgalactosaminyltransferase family. {ECO:0000256|ARBA:ARBA00009239,
CC ECO:0000256|RuleBase:RU364016}.
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DR EMBL; DS985263; EDV20124.1; -; Genomic_DNA.
DR RefSeq; XP_002117508.1; XM_002117472.1.
DR AlphaFoldDB; B3SB89; -.
DR EnsemblMetazoa; TriadT32618; TriadP32618; TriadG32618.
DR GeneID; 6758660; -.
DR KEGG; tad:TRIADDRAFT_32618; -.
DR CTD; 6758660; -.
DR eggNOG; KOG3588; Eukaryota.
DR HOGENOM; CLU_078350_0_0_1; -.
DR InParanoid; B3SB89; -.
DR OMA; RAATWIR; -.
DR OrthoDB; 2907318at2759; -.
DR PhylomeDB; B3SB89; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008376; F:acetylgalactosaminyltransferase activity; IEA:InterPro.
DR InterPro; IPR008428; Chond_GalNAc.
DR InterPro; IPR027791; Galactosyl_T_C.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR12369; CHONDROITIN SYNTHASE; 1.
DR PANTHER; PTHR12369:SF5; HEXOSYLTRANSFERASE; 1.
DR Pfam; PF05679; CHGN; 1.
DR Pfam; PF02709; Glyco_transf_7C; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|RuleBase:RU364016};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000009022};
KW Signal-anchor {ECO:0000256|RuleBase:RU364016};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU364016};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 108..180
FT /note="Galactosyltransferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02709"
FT REGION 189..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EDV20124.1"
SQ SEQUENCE 209 AA; 24555 MW; CB35DFDCCDB82F5A CRC64;
LSRYYKQTHD DHFTLIITDF NSTDVDIPAL LKSSSLKHHY MNIKTENFQF SRTIGINRAA
TWIRNDDAIL LMYDLHLTFP VDMLDNVRKR CKQGKAAYFP IVTRLGCGFA PRYPNGYPEL
WGFGISAFYK SDYVNVGGMN DQKFRFKWGG EDSDIADRTI SNSLEIERLL HPYFFHYYHR
QLPWKKSTAK KEKENKDINE PKIIKEIQA
//
