ID B3SCQ7_TRIAD Unreviewed; 700 AA.
AC B3SCQ7;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=SH2 domain-containing protein {ECO:0000259|PROSITE:PS50001};
GN ORFNames=TRIADDRAFT_62062 {ECO:0000313|EMBL:EDV19496.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV19496.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV19496.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV19496.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
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DR EMBL; DS985272; EDV19496.1; -; Genomic_DNA.
DR RefSeq; XP_002118013.1; XM_002117977.1.
DR AlphaFoldDB; B3SCQ7; -.
DR STRING; 10228.B3SCQ7; -.
DR EnsemblMetazoa; TriadT62062; TriadP62062; TriadG62062.
DR GeneID; 6759226; -.
DR KEGG; tad:TRIADDRAFT_62062; -.
DR CTD; 6759226; -.
DR HOGENOM; CLU_393978_0_0_1; -.
DR InParanoid; B3SCQ7; -.
DR OrthoDB; 3681543at2759; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0005942; C:phosphatidylinositol 3-kinase complex; IBA:GO_Central.
DR GO; GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; IBA:GO_Central.
DR GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IBA:GO_Central.
DR CDD; cd00173; SH2; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR PANTHER; PTHR19969:SF5; ADAPTER MOLECULE CRK; 1.
DR PANTHER; PTHR19969; SH2-SH3 ADAPTOR PROTEIN-RELATED; 1.
DR Pfam; PF00017; SH2; 1.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009022};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT DOMAIN 540..632
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 497..519
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 700 AA; 80438 MW; 6DD5E2EE8E1BA2C0 CRC64;
MDSDDDIYDC MLESSVKLVY DRILPKLERQ LPTKNFCKGA FKLGIIDYDK VLTASHEHIS
PDINRKILEY IDSEQLDDIK DWLSIMFDDE KCRPIAYEFI NELSEWKLEE LVENINIKDG
YILISDKLIS VSKLDSVQMD VDEPVIIVQD SISRKSFPIN KDHSVDVPIH AEDIKHKVNV
SVPFPIHYRP MSTEIDIFPL VTRFTAMASA SLVIKTWLQL PDSTSDQGNI RDCQLTCWIP
HYKQIKQLFC KSEKSVQQND KIIVARRINS DSTKFTEIGT KFSIDENKAT DDGVVVKCNC
SYQSVINWFW KIPQWLLDAA RLGPKYYYDY FRYPVQYFVG VKPMKDKPGH FTLIALVKNI
RCPLPSRIGD ELELLASSGD ETRLLSSGRL QINLAGDIKP LNGLIWVELL NKIAYFDGMY
SVTQFACMGH FDADNGIYSK GSVEFRYIDP GPNCHPDASN PDYNVENESV VVEFSYAIDH
EMTRKYSIIR GNVSDPETTG KVDARSPQPD PFTDTPMHNS KELSQNLSLI DSIEDTRHLW
YQEDMTKVNA IVFLQDQPIG TFVVRKSTRH HCEAISVKVT VDGNIGHFLF KNNSNEWSIA
DFERKFVSLE DLLTHYTNNK DKELQVKLRF PRPIHSNAKV EPETQSLPGE ISDCTMQHVS
IQDYNEVSNL EKFEYILSDS EENTGLSIEL WYQFTLIISK
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