ID B3VIL3_POPTN Unreviewed; 194 AA.
AC B3VIL3;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 22-FEB-2023, entry version 46.
DE RecName: Full=phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating) {ECO:0000256|ARBA:ARBA00013011};
DE EC=1.1.1.44 {ECO:0000256|ARBA:ARBA00013011};
DE Flags: Fragment;
OS Populus tremula (European aspen).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus.
OX NCBI_TaxID=113636 {ECO:0000313|EMBL:ACE96470.1};
RN [1] {ECO:0000313|EMBL:ACE96470.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Swl5-fra32 {ECO:0000313|EMBL:ACE96470.1};
RX PubMed=18716330; DOI=10.1534/genetics.108.090431;
RA Ingvarsson P.K.;
RT "Multilocus patterns of nucleotide polymorphism and the demographic history
RT of Populus tremula.";
RL Genetics 180:329-340(2008).
CC -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-
CC ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step
CC 3/3. {ECO:0000256|ARBA:ARBA00004874}.
CC -!- SIMILARITY: Belongs to the 6-phosphogluconate dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00008419}.
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DR EMBL; EU752607; ACE96470.1; -; Genomic_DNA.
DR AlphaFoldDB; B3VIL3; -.
DR UniPathway; UPA00115; UER00410.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:UniProtKB-EC.
DR GO; GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006114; 6PGDH_C.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006183; Pgluconate_DH.
DR PANTHER; PTHR11811; 6-PHOSPHOGLUCONATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11811:SF63; 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING 2; 1.
DR Pfam; PF00393; 6PGD; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PRINTS; PR00076; 6PGDHDRGNASE.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Gluconate utilization {ECO:0000256|ARBA:ARBA00023064};
KW Pentose shunt {ECO:0000256|ARBA:ARBA00023126}.
FT DOMAIN 6..142
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 147..194
FT /note="6-phosphogluconate dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00393"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACE96470.1"
FT NON_TER 194
FT /evidence="ECO:0000313|EMBL:ACE96470.1"
SQ SEQUENCE 194 AA; 21144 MW; 5ABE98DAD39B3192 CRC64;
TSKVDETVER AKKEGDLPLY GFHDPESFVK SIQKPRVIIM LVKAGSPVDQ TIKTLSAYLE
KGDCIIDGGN EWYENTERRE KAMAELGLLY LGMGVSGGEE GARNGPSMMP GGSFEAFKYI
EDILLKVAAQ VPDSGPCVTY IGKGGSGNFV KMVHNGIEYG DMQLIAEAYD VLKSVGKLSN
DELHSVFAEW NKGE
//
