ID   B4CTX1_9BACT            Unreviewed;       721 AA.
AC   B4CTX1;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   SubName: Full=Adenylate/guanylate cyclase {ECO:0000313|EMBL:EDY22009.1};
DE   Flags: Precursor;
GN   ORFNames=CfE428DRAFT_0134 {ECO:0000313|EMBL:EDY22009.1};
OS   Chthoniobacter flavus Ellin428.
OC   Bacteria; Verrucomicrobiota; Spartobacteria; Chthoniobacterales;
OC   Chthoniobacteraceae; Chthoniobacter.
OX   NCBI_TaxID=497964 {ECO:0000313|EMBL:EDY22009.1, ECO:0000313|Proteomes:UP000005824};
RN   [1] {ECO:0000313|EMBL:EDY22009.1, ECO:0000313|Proteomes:UP000005824}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ellin428 {ECO:0000313|EMBL:EDY22009.1,
RC   ECO:0000313|Proteomes:UP000005824};
RX   PubMed=21460085; DOI=10.1128/JB.00295-11;
RA   Kant R., van Passel M.W., Palva A., Lucas S., Lapidus A.,
RA   Glavina Del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S.,
RA   Larimer F.W., Land M.L., Hauser L., Sangwan P., de Vos W.M., Janssen P.H.,
RA   Smidt H.;
RT   "Genome sequence of Chthoniobacter flavus Ellin428, an aerobic
RT   heterotrophic soil bacterium.";
RL   J. Bacteriol. 193:2902-2903(2011).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EDY22009.1}.
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DR   EMBL; ABVL01000001; EDY22009.1; -; Genomic_DNA.
DR   RefSeq; WP_006977461.1; NZ_ABVL01000001.1.
DR   AlphaFoldDB; B4CTX1; -.
DR   STRING; 497964.CfE428DRAFT_0134; -.
DR   eggNOG; COG2114; Bacteria.
DR   InParanoid; B4CTX1; -.
DR   Proteomes; UP000005824; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   CDD; cd18774; PDC2_HK_sensor; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081:SF16; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC; 1.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005824};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        370..389
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          469..602
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   REGION          237..263
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   721 AA;  79714 MW;  20B08DDA1517034B CRC64;
     MKPTFGQVFA FSLVGLIVIL ALLFQLVSSS SRETITRSSE RIRNQVSSVI SERITQFLNE
     APATTWQFQR EVEQGLLDPH DGHSVEPALV SLLLADSDLG ELTFTYGDEQ GFDANGDVKL
     AAEPRGQWSV IRLSEDRERC RHVYQEHGAF VADRRDLGAK TAFASVPWVR ETGGNLPDPT
     THLTFTTPAR QDFHGRPVWS DLHWSQLDAD LPEAQRRVEV SVQQAITDAD WPLYRRPPRG
     FAGAASRREK SHPPNQANGQ RDPHLTFICD EDGRLITGLA PTDHLREDGD DLRIAPEGLS
     AEIRAAVHNA ILKEAVASET SVSGTFRANG EEYIATFRAL PRPQTQDWVI GIVVPRAFYF
     GQLAAMRERL LAVLLGVMIL LVICGGLILQ GVRRAQAQIT HESLKMNAFD FTPAPPSSPF
     RDVIDVLESQ EKAKAAMRAM SKYVPIDLVR RLYREKSEPM LGAEPLEVSI MFTDIKDFTT
     LCERLQPNEL ADALGRYLEV MAGIIQRECG GTIDKFIGDA IMTFWNAPEP VVDHARMACR
     AALRCREAGA RLAQSADWGT WPAFGTRFGL HCAPALIGHF GARDRMNYTA IGDAVNLASR
     LEGLNKQYGT SIIVSETVVN HCGDDFVFRL LDRVAVKGKS EAIRIFELLG VKGEAGELRE
     TVALYEKAFA AYSTRDFAGA IEILSGQQSD PPSAALLGRC RGYLEEPPAE GWDGVYVSKT
     K
//