ID   B4DL35_HUMAN            Unreviewed;       289 AA.
AC   B4DL35; E7EMR8;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   SubName: Full=cDNA FLJ51230, highly similar to Abhydrolase domain-containing protein 2 {ECO:0000313|EMBL:BAG59397.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAG59397.1};
RN   [1] {ECO:0000313|EMBL:BAG59397.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Tongue {ECO:0000313|EMBL:BAG59397.1};
RA   Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A.,
RA   Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y.,
RA   Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.,
RA   Sugano S., Nomura N., Isogai T.;
RT   "NEDO human cDNA sequencing project focused on splicing variants.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC       pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. AB hydrolase 4
CC       family. {ECO:0000256|ARBA:ARBA00010884}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AK296827; BAG59397.1; -; mRNA.
DR   AlphaFoldDB; B4DL35; -.
DR   ESTHER; human-ABHD2; abh_upf0017.
DR   MEROPS; S33.019; -.
DR   MaxQB; B4DL35; -.
DR   PeptideAtlas; B4DL35; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR000952; AB_hydrolase_4_CS.
DR   InterPro; IPR012020; ABHD4.
DR   PANTHER; PTHR10794; ABHYDROLASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR10794:SF45; MONOACYLGLYCEROL LIPASE ABHD2; 1.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   PIRSF; PIRSF005211; Ab_hydro_YheT; 2.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS01133; UPF0017; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:BAG59397.1};
KW   Serine esterase {ECO:0000256|ARBA:ARBA00022487}.
FT   DOMAIN          63..246
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000259|Pfam:PF00561"
SQ   SEQUENCE   289 AA;  32925 MW;  74364EE4FF447751 CRC64;
     MNAMLETPEL PAVFDGVKLA AVAAVLYVIV RCLNLKSPTA PPDLYFQDSG LSRFLLKSCP
     LLTQLVVVGF SLGGNIVCKY LGETQANQEK VLCCVSVCQG YSALRAQETF MQWDQCRRFY
     NFLMADNMKK IILSHRQALF GDHVKKPQSL EDTDLSRLYT ATSLMQIDDN VMRKFHGYNS
     LKEYYEEESC MRYLHRIYVP LMLVNAADDP LVHESLLTIP KSLSEKRENV MFVLPLHGGH
     LGFFEGSVLF PEPLTWMDKL VVEYANAICQ WERNKLQCSD TEQVEADLE
//