ID B4DN79_HUMAN Unreviewed; 461 AA.
AC B4DN79;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 24-JAN-2024, entry version 57.
DE SubName: Full=cDNA FLJ53367, highly similar to Transmembrane glycoprotein NMB {ECO:0000313|EMBL:BAG60141.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|EMBL:BAG60141.1};
RN [1] {ECO:0000313|EMBL:BAG60141.1}
RP NUCLEOTIDE SEQUENCE.
RA Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A.,
RA Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y.,
RA Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.,
RA Sugano S., Nomura N., Isogai T.;
RT "NEDO human cDNA sequencing project focused on splicing variants.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the PMEL/NMB family.
CC {ECO:0000256|ARBA:ARBA00025776}.
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DR EMBL; AK297803; BAG60141.1; -; mRNA.
DR AlphaFoldDB; B4DN79; -.
DR PeptideAtlas; B4DN79; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00146; PKD; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR045219; PKAT.
DR InterPro; IPR046846; PKAT_KLD.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR PANTHER; PTHR11861; MELANOCYTE PROTEIN PMEL 17-RELATED; 1.
DR PANTHER; PTHR11861:SF11; TRANSMEMBRANE GLYCOPROTEIN NMB; 1.
DR Pfam; PF20433; PKAT_KLD; 1.
DR Pfam; PF18911; PKD_4; 1.
DR SMART; SM00089; PKD; 1.
DR SUPFAM; SSF49299; PKD domain; 1.
DR PROSITE; PS50093; PKD; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|EMBL:BAG60141.1};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..461
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002803713"
FT TRANSMEM 389..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 178..216
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT REGION 221..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..240
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 461 AA; 51142 MW; 282709997BB8FB23 CRC64;
MECLYYFLGF LLLAARLPLD AAKQAGLSAD PYVYNWTAWS EDSDGENGTG QSHHNVFPDG
KPFPHHPGWR RWNFIYVFHT LGQYFQKLGR CSVRVPVNTA NVTLGPQLME VTVYRRHGRA
YVPIAQVKDV YVVTDQIPVF VTMFQKNDRN SSDETFLKDL PIMFDVLIHD PSHFLNYSTI
NYKWSFGDNT GLFVSTNHTV NHTYVLNGTF SLNLTVKAAA PGPCPPPPPP PRPSKPTPSL
GPAGDNPLEL SRIPDENCQI NRYGHFQATI TIVEGILEVN IIQMTDVLMP VPWPESSLID
FVVTCQGSIP TEVCTIISDP TCEITQNTVC SPVDVDEMCL LTVRRTFNGS GTYCVNLTLG
DDTSLALTST LISVPDRDPA SPLRMANSAL ISVGCLAIFV TVISLLVYKK HKEYNPIENS
PGNVVRSKGL SVFLNRAKAV FFPGNQEKDP LLKNQEFKGV S
//
