ID B4EHS6_BURCJ Unreviewed; 673 AA.
AC B4EHS6;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Betaine/carnitine/choline family transporter {ECO:0000313|EMBL:CAR55142.1};
GN ORFNames=BCAM1286 {ECO:0000313|EMBL:CAR55142.1};
OS Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 /
OS NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=216591 {ECO:0000313|EMBL:CAR55142.1, ECO:0000313|Proteomes:UP000001035};
RN [1] {ECO:0000313|EMBL:CAR55142.1, ECO:0000313|Proteomes:UP000001035}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 /
RC CF5610 {ECO:0000313|Proteomes:UP000001035};
RX PubMed=18931103; DOI=10.1128/JB.01230-08;
RA Holden M.T., Seth-Smith H.M., Crossman L.C., Sebaihia M., Bentley S.D.,
RA Cerdeno-Tarraga A.M., Thomson N.R., Bason N., Quail M.A., Sharp S.,
RA Cherevach I., Churcher C., Goodhead I., Hauser H., Holroyd N., Mungall K.,
RA Scott P., Walker D., White B., Rose H., Iversen P., Mil-Homens D.,
RA Rocha E.P., Fialho A.M., Baldwin A., Dowson C., Barrell B.G., Govan J.R.,
RA Vandamme P., Hart C.A., Mahenthiralingam E., Parkhill J.;
RT "The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of
RT cystic fibrosis patients.";
RL J. Bacteriol. 191:261-277(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the BCCT transporter (TC 2.A.15) family.
CC {ECO:0000256|ARBA:ARBA00005658}.
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DR EMBL; AM747721; CAR55142.1; -; Genomic_DNA.
DR RefSeq; WP_012493275.1; NC_011001.1.
DR AlphaFoldDB; B4EHS6; -.
DR KEGG; bcj:BCAM1286; -.
DR eggNOG; COG1292; Bacteria.
DR HOGENOM; CLU_010118_3_1_4; -.
DR BioCyc; BCEN216591:G1G1V-5294-MONOMER; -.
DR Proteomes; UP000001035; Chromosome 2.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071705; P:nitrogen compound transport; IEA:InterPro.
DR InterPro; IPR018093; BCCT_CS.
DR InterPro; IPR000060; BCCT_transptr.
DR NCBIfam; TIGR00842; bcct; 1.
DR PANTHER; PTHR30047:SF7; HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN; 1.
DR PANTHER; PTHR30047; HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN-RELATED; 1.
DR Pfam; PF02028; BCCT; 1.
DR PROSITE; PS01303; BCCT; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 54..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 410..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 451..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 478..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 673 AA; 73372 MW; 5055B9B7F90BA649 CRC64;
MPDSRPMPRT TFKPQVVLLA LAVIGALLVV CALHPSEAGA LFSAGQQWVI ARFDWFYVLA
VTGFLVFLVL IAASDFGNIR LGPDDAEPEF SFVSWTAMLF AAGMGIGLMY FGVGEPMQHF
LKPPTVDPGT PAAAREAMLM TFFHWGFHAW AIYGLMGLVL AYFGFRYNLP LTLRSGLYPV
LRERINGWIG HTVDAFALVG TVAGIATTLG YGVMQLSAGL HTVAGWDTGS NLFRIGLVAV
VVILAGVSAA TGLDKGVRRL SELNLLLAFL LLAFVVVAGP TAFLLRALGD NIGQYLSSLV
DLSFRTYAYA PPREEGWFGG WTILYWAWWV SWSPFVGMFI ARISRGRTIR QFVIGVLLVP
TAFNLVWMTV FGNSAIWLDT HGAAGALAQT ATNVDALLFR FFDFLPLPQL LSIVAIVLIA
VFFVTSADSG AFVIDQIATR GSAQSPVWQR LFWAALLGVT AAVLLVAGGL GALQAMTLIA
ALPVAIIMLA LCYGLWRGLA ADRAHYSQDV APATSFWTGQ HWRHRLTHIL RQTTEAEARQ
FVAETVEPAL RKVAAELRAS GVDAHVQRDG DDAVRLTVPT AEHRDFVYGV RVTAKSAAAF
LVREAAEPDE ARAHVYGIVT FFEDGRLGYD VEYLRGDEVI ADVLRQYERY VSLAADKRTH
LLSRAPGHAT EAE
//
