ID B4ETT2_PROMH Unreviewed; 316 AA.
AC B4ETT2;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE RecName: Full=Universal stress protein E {ECO:0000256|ARBA:ARBA00040919};
GN Name=uspE {ECO:0000313|EMBL:CAR42558.1};
GN OrderedLocusNames=PMI1202 {ECO:0000313|EMBL:CAR42558.1};
OS Proteus mirabilis (strain HI4320).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Proteus.
OX NCBI_TaxID=529507 {ECO:0000313|EMBL:CAR42558.1, ECO:0000313|Proteomes:UP000008319};
RN [1] {ECO:0000313|EMBL:CAR42558.1, ECO:0000313|Proteomes:UP000008319}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HI4320 {ECO:0000313|EMBL:CAR42558.1,
RC ECO:0000313|Proteomes:UP000008319};
RX PubMed=18375554; DOI=10.1128/JB.01981-07;
RA Pearson M.M., Sebaihia M., Churcher C., Quail M.A., Seshasayee A.S.,
RA Luscombe N.M., Abdellah Z., Arrosmith C., Atkin B., Chillingworth T.,
RA Hauser H., Jagels K., Moule S., Mungall K., Norbertczak H.,
RA Rabbinowitsch E., Walker D., Whithead S., Thomson N.R., Rather P.N.,
RA Parkhill J., Mobley H.L.;
RT "Complete genome sequence of uropathogenic Proteus mirabilis, a master of
RT both adherence and motility.";
RL J. Bacteriol. 190:4027-4037(2008).
RN [2] {ECO:0007829|PDB:3OLQ}
RP X-RAY CRYSTALLOGRAPHY (1.82 ANGSTROMS).
RA Tan K., Chhor G., Bearden J., Joachimiak A.;
RT "The crystal structure of a universal stress protein E from Proteus
RT mirabilis HI4320.";
RL Submitted (AUG-2010) to the PDB data bank.
RN [3] {ECO:0007829|PDB:4WY2}
RP X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS).
RA Shumilin I.A., Minor W.;
RT "Crystal structure of universal stress protein E from Proteus mirabilis
RT incomplex withUDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetyl-alpha-
RT glucosamine.";
RL Submitted (NOV-2014) to the PDB data bank.
CC -!- FUNCTION: Required for resistance to DNA-damaging agents.
CC {ECO:0000256|ARBA:ARBA00037131}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the universal stress protein A family.
CC {ECO:0000256|ARBA:ARBA00008791}.
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DR EMBL; AM942759; CAR42558.1; -; Genomic_DNA.
DR RefSeq; WP_004248016.1; NC_010554.1.
DR PDB; 3OLQ; X-ray; 1.82 A; A=1-316.
DR PDB; 4WY2; X-ray; 1.80 A; A=1-316.
DR PDBsum; 3OLQ; -.
DR PDBsum; 4WY2; -.
DR AlphaFoldDB; B4ETT2; -.
DR SMR; B4ETT2; -.
DR DNASU; 6802550; -.
DR EnsemblBacteria; CAR42558; CAR42558; PMI1202.
DR GeneID; 6802550; -.
DR KEGG; pmr:PMI1202; -.
DR eggNOG; COG0589; Bacteria.
DR HOGENOM; CLU_049301_1_2_6; -.
DR EvolutionaryTrace; B4ETT2; -.
DR Proteomes; UP000008319; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd00293; USP_Like; 2.
DR Gene3D; 3.40.50.12370; -; 1.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR47892; UNIVERSAL STRESS PROTEIN E; 1.
DR PANTHER; PTHR47892:SF1; UNIVERSAL STRESS PROTEIN E; 1.
DR Pfam; PF00582; Usp; 2.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 2.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:3OLQ, ECO:0007829|PDB:4WY2};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490}.
FT DOMAIN 4..146
FT /note="UspA"
FT /evidence="ECO:0000259|Pfam:PF00582"
FT DOMAIN 218..301
FT /note="UspA"
FT /evidence="ECO:0000259|Pfam:PF00582"
SQ SEQUENCE 316 AA; 35954 MW; 4B9DBFA5A773165A CRC64;
MEKYQNLLVV IDPNQDDQPA LRRAVYIVQR NGGRIKAFLP VYDLSYDMTT LLSPDERNAM
RKGVINQKTA WIKQQARYYL EAGIQIDIKV IWHNRPYEAI IEEVITDKHD LLIKMAHQHD
KLGSLIFTPL DWQLLRKCPA PVWMVKDKEW PEYGTIVVAA NLSNEESYHD ALNLKLIELT
NDLSHRIQKD PDVHLLSAYP VAPINIAIEL PDFDPNLYNN ALRGQHLIAM KELRQKFSIP
EEKTHVKEGL PEQVIPQVCE ELNAGIVVLG ILGRTGLSAA FLGNTAEQLI DHIKCDLLAI
KPDGFTCPIT VDSDNE
//
