ID B4FW72_MAIZE Unreviewed; 517 AA.
AC B4FW72;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 24-JAN-2024, entry version 70.
DE SubName: Full=Folate-biopterin transporter 1 chloroplastic {ECO:0000313|EMBL:ONM51606.1};
GN Name=100273543 {ECO:0000313|EnsemblPlants:Zm00001eb301040_P002};
GN ORFNames=ZEAMMB73_Zm00001d018907 {ECO:0000313|EMBL:ONM51606.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577 {ECO:0000313|EMBL:ACF86365.1};
RN [1] {ECO:0000313|EMBL:ACF86365.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=B73 {ECO:0000313|EMBL:ACF86365.1};
RX PubMed=19936069; DOI=10.1371/journal.pgen.1000740;
RA Soderlund C., Descour A., Kudrna D., Bomhoff M., Boyd L., Currie J.,
RA Angelova A., Collura K., Wissotski M., Ashley E., Morrow D., Fernandes J.,
RA Walbot V., Yu Y.;
RT "Sequencing, mapping, and analysis of 27,455 maize full-length cDNAs.";
RL PLoS Genet. 5:E1000740-E1000740(2009).
RN [2] {ECO:0000313|EMBL:ONM51606.1, ECO:0000313|Proteomes:UP000007305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb301040_P002,
RC ECO:0000313|Proteomes:UP000007305};
RC TISSUE=Seedling {ECO:0000313|EMBL:ONM51606.1};
RG Maize Genome Sequencing Project;
RA Ware D.;
RT "Update maize B73 reference genome by single molecule sequencing
RT technologies.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:Zm00001eb301040_P002}
RP IDENTIFICATION.
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb301040_P002};
RG EnsemblPlants;
RL Submitted (MAY-2021) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Folate-
CC biopterin transporter (TC 2.A.71) family.
CC {ECO:0000256|ARBA:ARBA00007015}.
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DR EMBL; BT041360; ACF86365.1; -; mRNA.
DR EMBL; CM007650; ONM51606.1; -; Genomic_DNA.
DR EMBL; CM007650; ONM51607.1; -; Genomic_DNA.
DR RefSeq; NP_001141433.1; NM_001147961.1.
DR AlphaFoldDB; B4FW72; -.
DR IntAct; B4FW72; 2.
DR PaxDb; 4577-GRMZM2G027603_P01; -.
DR EnsemblPlants; Zm00001eb301040_T002; Zm00001eb301040_P002; Zm00001eb301040.
DR EnsemblPlants; Zm00001eb301040_T003; Zm00001eb301040_P003; Zm00001eb301040.
DR GeneID; 100273543; -.
DR Gramene; Zm00001eb301040_T002; Zm00001eb301040_P002; Zm00001eb301040.
DR Gramene; Zm00001eb301040_T003; Zm00001eb301040_P003; Zm00001eb301040.
DR KEGG; zma:100273543; -.
DR eggNOG; ENOG502QPYM; Eukaryota.
DR HOGENOM; CLU_018563_3_1_1; -.
DR InParanoid; B4FW72; -.
DR OrthoDB; 241511at2759; -.
DR Proteomes; UP000007305; Chromosome 7.
DR ExpressionAtlas; B4FW72; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd17484; MFS_FBT; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR039309; BT1.
DR InterPro; IPR004324; FBT.
DR InterPro; IPR036259; MFS_trans_sf.
DR NCBIfam; TIGR00788; fbt; 1.
DR PANTHER; PTHR31585; FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC; 1.
DR PANTHER; PTHR31585:SF0; FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC; 1.
DR Pfam; PF03092; BT1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007305};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 95..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 445..471
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 483..502
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 23..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..70
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 517 AA; 55413 MW; 2D0C9DE3F4E5FCA7 CRC64;
MASVGWAARD AYDEEAAVRR PLELEGRGVA ASSSDHRPGG NVMPRYQVGS TKGDSSSRRH
SEEWRQPSTD DVRMSKPGSR YFTAFGVDLS PDNMAVAIVY FVQGVLGLAR LAVSFYLKDD
LHLDPAETAV VSGFSSLPWL IKPLYGFISD SIPLFGYRRR SYLFLSGLLG ALSWSLMATV
VSSKYSAAFS ILLGSLSVAF SDVVVDSMVV ERARGESQST SGSLQSLCWG SSAFGGIVSA
YFSGSLVDTY GVRFVFGVTA FLPLMTSAVA VLVNEHGIPS GEHNTFLSGS GFVESSKQHV
RQLWASVKQP NILLPTLFIF LWQATPQSDS AMFFFITNKL GFTPEFLGRV KLVTSFASLL
GVGLYNYFLK EVALRKIFLV TTIIGSALGM TQVLLVTGLN RQLGISDEWF SIGDSLIITV
LGQASFMPVL VLAAKLCPPG MEATLFATLM SISNAGSVTG GLVGAGLTRI FGVTRDTFGN
LPLLIVVCNL SSLLPLPLLG LLPEGSGDTD NGETKNN
//
