ID B4MGQ6_DROVI Unreviewed; 1772 AA.
AC B4MGQ6;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 2.
DT 24-JAN-2024, entry version 79.
DE SubName: Full=Uncharacterized protein, isoform A {ECO:0000313|EMBL:EDW57122.2};
GN Name=Dvir\GJ16045 {ECO:0000313|EMBL:EDW57122.2};
GN ORFNames=Dvir_GJ16045 {ECO:0000313|EMBL:EDW57122.2};
OS Drosophila virilis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7244 {ECO:0000313|EMBL:EDW57122.2, ECO:0000313|Proteomes:UP000008792};
RN [1] {ECO:0000313|EMBL:EDW57122.2, ECO:0000313|Proteomes:UP000008792}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15010-1051.87 {ECO:0000313|Proteomes:UP000008792};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- SIMILARITY: Belongs to the DIP2 family.
CC {ECO:0000256|ARBA:ARBA00007735}.
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DR EMBL; CH940682; EDW57122.2; -; Genomic_DNA.
DR RefSeq; XP_002060309.2; XM_002060273.2.
DR SMR; B4MGQ6; -.
DR EnsemblMetazoa; FBtr0231970; FBpp0230462; FBgn0203230.
DR GeneID; 6636836; -.
DR KEGG; dvi:6636836; -.
DR eggNOG; KOG3628; Eukaryota.
DR HOGENOM; CLU_001345_0_0_1; -.
DR OrthoDB; 3994129at2759; -.
DR Proteomes; UP000008792; Unassembled WGS sequence.
DR CDD; cd05905; Dip2; 2.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 2.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR037337; Dip2-like_dom.
DR InterPro; IPR010506; DMAP1-bd.
DR PANTHER; PTHR22754:SF32; DISCO-INTERACTING PROTEIN 2; 1.
DR PANTHER; PTHR22754; DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED; 1.
DR Pfam; PF00501; AMP-binding; 2.
DR Pfam; PF06464; DMAP_binding; 1.
DR SMART; SM01137; DMAP_binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR PROSITE; PS51912; DMAP1_BIND; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008792}.
FT DOMAIN 13..121
FT /note="DMAP1-binding"
FT /evidence="ECO:0000259|PROSITE:PS51912"
FT REGION 105..201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 214..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 121..139
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 252..266
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 286..313
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1772 AA; 194084 MW; 6C7B3EABE40D3A6C CRC64;
MSATAANFLG MDLVSSLPSD VREKLAELDL ELSEGDITQK GYEKKRSKLL QPYLKKQELN
DVEKSKNLLP PPYYNIKESN NSISNVNNDG VIVSSEGYSY VTEVPSLPSS QQRHSKKTEF
HQPSSAISIS SSTPQSGGGV PGYENMRPQG GAVGDPGYQN TREPNTFQNH ASHPPTNSSQ
NRQRRTQRKV THNEKRYHSE VRQEAVQQAL AALKGRPKPS LPMPSKRSSV LNRSPGCNDE
LDSSSDDESI PEELISPDKE YNYPRDHISK NMLPPDPIIK PPIRESSMIA QQQHLRHDVK
QSQAPSQKYS LSGSAAERRP PQILPPLPTS DTSSTESPPI GYKRDNEFTD KAYKQKHFNA
PDITQFNNAH RIADRVTRYV NVSQTELNET DANGKWKVSA KIQQLLNTLK RPKRRPLPEF
YEDNDIELEI AANPKDPNAP KPEGSTMTPV QGEQLSIPAG LPRTLECALQ RYGMNSFKSS
MATVLDPNGK ITTTLTYGKL LSRAQKIAYA LSTKIFSKGP EQVTLKPGDR VALVYPNNDP
LSFITAWYGC MFRGLVPLPI ELPLSSSDTP PQQVGFLLSS CGITVALTSE ACLKGLPKSA
TGEIAKLKGW PRLQWFVTEH LPKPPKDFNV GNLRVEDTAA AYIEYTTDKE GSVMGITVSR
AAMINHCRAL TMACHYTEGE TIVCVLDFKR EVGLWHAVLT SILNGMHVVF IPYALMKLRP
SSWMQLITKH RASCCLVKSR DLHWGLLATK DHKDISLASL RMLLIADGAN PWSLSSCDQF
LNVFQAKGLR SDAICPCASS SEVFTVSLRR PGRSSTTGFC QSATGRGVLS MAALSHGVVR
VDSEDSLTSL TLQDCGQVMP AAQMVVVRSE GAPVLCKTDQ VGEICVTSGS TGASYFGLDG
MTNSTFKVQP LIEDPEQPKD GGGTIASTPK PISDEYYVRS GLLGFLGPGG LVFVCGSRDG
LMTVTGRKHN ADDIIATVLA VEPMRFIYRG RIAVFSIKVL RDERVCVIAE QRPDCSEEES
FQWMSRVLQA VDSIHQVGIY CLALVPPNHL PKTPLGGIHL CEARRRFLEG SLHPANVLMC
PHTCVTNLPK PRELHQDTGV GPASVMVGNL VQGNRLAVAH GRDVGMAEDG ERKPQIITGV
LRWRANTSPD HIIFTLLNAK GAIAKTLTCS ELHKRAEKIA ALLQERGKIE PGDHVALIFP
PGLDLLCAFY GCLYLGAIPI TIRPPHPQNL ITTLPTVRMI VDVSKSGIVL SIQPIIKLLK
SREAASSIDP KTWPPILDID DNPKRKLAGI ATVSLDSSAY LDFSVSTCGR LSGVNITHRS
LSSLCASLKL ACELYPSRHV ALCLDPYCGL GFVMWTLIGV YSGHHSILIA PYEVEANPSL
WLSTLSQHRV RDTFCSYGVI ELCTKALSNS VPSLKQRNVD LRCVRTCVVV GEERPRVTLT
QQFCKLFQGL GLNTRCVSTS FGCRVNPAIC VQGASSAESA QVYVDLRALR NNRVALVERG
APNSLCLIES GKLLPGVKVI IANPETKGHC GDSHLGEIWV QAPHNANGYF TIYGDETDYN
DHFNAKLVTG ATSEMYARTG YLGFLRRTEC SQAASILDET TPSVASRDSD TESLNSMSQL
QLNFSNTSLG GNSEQSLMGG AVNSNDQELH DAVYVVGALD EVISLRGMNY HPIDIENSVL
RCHKKIAECA VFTWTNLLVV VVELDGNESE ALDLVPLVTN TVLEEHQLIV GVVVVVDPGV
VPINSRGEKQ RMHLRDGFLA DQLDPIYVAY NM
//
