ID B4UB41_ANASK Unreviewed; 649 AA.
AC B4UB41;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN OrderedLocusNames=AnaeK_0447 {ECO:0000313|EMBL:ACG71689.1};
OS Anaeromyxobacter sp. (strain K).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Anaeromyxobacteraceae; Anaeromyxobacter.
OX NCBI_TaxID=447217 {ECO:0000313|EMBL:ACG71689.1, ECO:0000313|Proteomes:UP000001871};
RN [1] {ECO:0000313|EMBL:ACG71689.1, ECO:0000313|Proteomes:UP000001871}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K {ECO:0000313|EMBL:ACG71689.1,
RC ECO:0000313|Proteomes:UP000001871};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C.,
RA Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikiva G.,
RA Beliaev A.;
RT "Complete sequence of Anaeromyxobacter sp. K.";
RL Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; CP001131; ACG71689.1; -; Genomic_DNA.
DR RefSeq; WP_012524522.1; NC_011145.1.
DR AlphaFoldDB; B4UB41; -.
DR KEGG; ank:AnaeK_0447; -.
DR HOGENOM; CLU_023030_3_0_7; -.
DR OrthoDB; 9803139at2; -.
DR Proteomes; UP000001871; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd15491; selB_III; 1.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09106; SelB-wing_2; 1.
DR Pfam; PF09107; SelB-wing_3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 3.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:ACG71689.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000313|EMBL:ACG71689.1}.
FT DOMAIN 1..176
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 649 AA; 67786 MW; DCAA9C7E7203864F CRC64;
MKRVVIGTAG HIDHGKTSLV RALTGIDTDR LRDEKRRGIT IELGFAHLAL PDGSVAGVVD
VPGHERFVRS MAAGAGGIDL VVLVIAADEG VMPQTREHLD ICRLLGVPRG LVAVTKADLL
PELGADWLPL LEQDVREVTR GTFLEGAPIV PVSSATGEGL DALRAALAAL AAEVPERPTD
GPLFLPIDRA FSMKGFGTVV TGTLLSGQIA EGDAAALLPA SPGGDGLRVR SVQVHGKPTP
RALAGQRTAV NLPGIEPAAI RRGQVLVHPG VVPPSSILDA ELTLLAAAPK PLRHRAKLLL
HVGTAQVPAV ISLLDRAELA PGATAHAQLR LAEPAAALPG QRFILRGFAV LEGRGKTVGG
GRVLAVAAPK RRRGRPESLA QLAVLAGADP EARLATVLAM AGPAGLDLPA LVGRTALSPK
AAQATLDRLG ARGGAVLFDR ERRAYVAGTV AQELTRRMAA AVAAFHRDHP LAAGMGREAL
RGKLPPVTDP RLFQRLLAHA AERGELVVEG DAVREKGHAA ASGESAGGAL KEKVAAALAK
GGLTPPWLAE LPGAVGASAP DVQAVLKLLA AEGRALRVSS ELYFDAAAVK TLEAKLVAWL
RERRQITTQE FKDLVGATRK HVIPLAEFFD REKVTLRVGE KRVLRGEGR
//
