ID   B5B958_LISMN            Unreviewed;       154 AA.
AC   B5B958;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=succinyl-diaminopimelate desuccinylase {ECO:0000256|ARBA:ARBA00011921};
DE            EC=3.5.1.18 {ECO:0000256|ARBA:ARBA00011921};
DE   Flags: Fragment;
GN   Name=dapE {ECO:0000313|EMBL:CAQ77390.1};
OS   Listeria monocytogenes.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=1639 {ECO:0000313|EMBL:CAQ77390.1};
RN   [1] {ECO:0000313|EMBL:CAQ77390.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Ragon M., Wirth T., Hollandt F., Lavenir R., Lecuit M., Le Monnier A.,
RA   Brisse S.;
RT   "A new perspective on Listeria monocytogenes evolution.";
RL   PLoS Pathog. 4:e1000146-e1000146(2008).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate =
CC         (2S,6S)-2,6-diaminoheptanedioate + succinate; Xref=Rhea:RHEA:22608,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:30031, ChEBI:CHEBI:57609,
CC         ChEBI:CHEBI:58087; EC=3.5.1.18;
CC         Evidence={ECO:0000256|ARBA:ARBA00001246};
CC   -!- COFACTOR:
CC       Name=Co(2+); Xref=ChEBI:CHEBI:48828;
CC         Evidence={ECO:0000256|ARBA:ARBA00001941};
CC   -!- PATHWAY: Amino-acid biosynthesis; L-lysine biosynthesis via DAP
CC       pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate
CC       (succinylase route): step 3/3. {ECO:0000256|ARBA:ARBA00005130}.
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DR   EMBL; FM180292; CAQ77390.1; -; Genomic_DNA.
DR   AlphaFoldDB; B5B958; -.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR001261; ArgE/DapE_CS.
DR   InterPro; IPR002933; Peptidase_M20.
DR   PANTHER; PTHR43808; ACETYLORNITHINE DEACETYLASE; 1.
DR   PANTHER; PTHR43808:SF8; M20_DIMER DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01546; Peptidase_M20; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR   PROSITE; PS00758; ARGE_DAPE_CPG2_1; 1.
DR   PROSITE; PS00759; ARGE_DAPE_CPG2_2; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CAQ77390.1"
FT   NON_TER         154
FT                   /evidence="ECO:0000313|EMBL:CAQ77390.1"
SQ   SEQUENCE   154 AA;  16724 MW;  9DEEC5084E298958 CRC64;
     LQKLLAEHGI ESEKVKYDVD RASLVSEIGS SDEKVLAFSG HMDVVDAGDV SKWKFPPFEA
     AEHEGKIYGR GATDMKSGLA AMIIAMIELH EEKQKLNGKI RLLATVGEEV GELGAEQLTQ
     KGYADDLDGL IIGEPSGHRI VYAHKGSINY TVKS
//