ID B5F5X4_SALA4 Unreviewed; 400 AA.
AC B5F5X4;
DT 14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2008, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=cysteine-S-conjugate beta-lyase {ECO:0000256|ARBA:ARBA00012224};
DE EC=4.4.1.13 {ECO:0000256|ARBA:ARBA00012224};
GN OrderedLocusNames=SeAg_B1608 {ECO:0000313|EMBL:ACH52209.1};
OS Salmonella agona (strain SL483).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=454166 {ECO:0000313|EMBL:ACH52209.1, ECO:0000313|Proteomes:UP000008819};
RN [1] {ECO:0000313|EMBL:ACH52209.1, ECO:0000313|Proteomes:UP000008819}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SL483 {ECO:0000313|EMBL:ACH52209.1,
RC ECO:0000313|Proteomes:UP000008819};
RX PubMed=21602358; DOI=10.1128/JB.00297-11;
RA Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G.,
RA Leclerc J.E., Ravel J., Cebula T.A.;
RT "Comparative genomics of 28 Salmonella enterica isolates: evidence for
RT CRISPR-mediated adaptive sublineage evolution.";
RL J. Bacteriol. 193:3556-3568(2011).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the class-II pyridoxal-phosphate-dependent
CC aminotransferase family. MalY/PatB cystathionine beta-lyase subfamily.
CC {ECO:0000256|ARBA:ARBA00037974}.
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DR EMBL; CP001138; ACH52209.1; -; Genomic_DNA.
DR RefSeq; WP_000347153.1; NC_011149.1.
DR AlphaFoldDB; B5F5X4; -.
DR KEGG; sea:SeAg_B1608; -.
DR HOGENOM; CLU_017584_15_0_6; -.
DR Proteomes; UP000008819; Chromosome.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR027619; C-S_lyase_PatB-like.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; TIGR04350; C_S_lyase_PatB; 1.
DR PANTHER; PTHR43525; PROTEIN MALY; 1.
DR PANTHER; PTHR43525:SF1; PROTEIN MALY; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:ACH52209.1};
KW Transferase {ECO:0000313|EMBL:ACH52209.1}.
FT DOMAIN 36..384
FT /note="Aminotransferase class I/classII"
FT /evidence="ECO:0000259|Pfam:PF00155"
SQ SEQUENCE 400 AA; 45110 MW; 117C5901D5F6353C CRC64;
MDFNQIINRN NTGSVKWDFI ERHFGDGAGK LLPMWVSDFD FACPPEVQAA LHQRIEHGVF
GYSERDEAYF NALLHWFSSR HQLTLKQEWV CSVEGVVPGL ALLVQMLTHP GDGVVVQGPY
YGSFAKIITL NGRKLLENPL SESPDDGYQM DFCQLERLFR HERPPLMILC NPHNPTGRCW
SANELEQLLL LCEAYDVTLI SDEIWADLLL PGETFTSVLH LGERWHKRVI SATAASKTFG
LSSLRISNFL IPDPTLRQRF LSRLDAHGLD VFNALSVQAA TIAWNESRQW LDSLLDYLAE
NRRWFVEQAT EYLPWARIVP AQGTYLLWMD CKKLGLDDEQ LKWVMADVAG IAPSMGSGFG
PAGSGFIRLN LGCPRTYLEM AIDGLKRISV KTIKGIPIGG
//
