ID   B5GBC4_STRSH            Unreviewed;       327 AA.
AC   B5GBC4;
DT   14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2008, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   SubName: Full=Aldo/keto reductase family oxidoreductase {ECO:0000313|EMBL:EDY43620.2};
GN   ORFNames=SSBG_01582 {ECO:0000313|EMBL:EDY43620.2};
OS   Streptomyces sp. (strain SPB074).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=465543 {ECO:0000313|EMBL:EDY43620.2, ECO:0000313|Proteomes:UP000002779};
RN   [1] {ECO:0000313|Proteomes:UP000002779}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SPB074 {ECO:0000313|Proteomes:UP000002779};
RG   The Broad Institute Genome Sequencing Platform;
RA   Fischbach M., Ward D., Young S., Jaffe D., Gnerre S., Berlin A., Heiman D.,
RA   Hepburn T., Sykes S., Alvarado L., Kodira C.D., Straight P., Clardy J.,
RA   Hung D., Kolter R., Mekalanos J., Walker S., Walsh C.T., Lander E.,
RA   Galagan J., Nusbaum C., Birren B.;
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EDY43620.2, ECO:0000313|Proteomes:UP000002779}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SPB074 {ECO:0000313|Proteomes:UP000002779};
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Microbial Sequencing Center;
RA   Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA   Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA   Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA   Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA   Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA   Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA   Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA   Haas B., Nusbaum C., Birren B.;
RT   "The genome sequence of Streptomyces sp. strain SPB74.";
RL   Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GG770539; EDY43620.2; -; Genomic_DNA.
DR   RefSeq; WP_008747261.1; NZ_GG770539.1.
DR   AlphaFoldDB; B5GBC4; -.
DR   OrthoDB; 9768793at2; -.
DR   Proteomes; UP000002779; Unassembled WGS sequence.
DR   CDD; cd19086; AKR_AKR11C1; 1.
DR   Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR   InterPro; IPR023210; NADP_OxRdtase_dom.
DR   InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR   PANTHER; PTHR43312:SF1; ALDO_KET_RED DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43312; D-THREO-ALDOSE 1-DEHYDROGENASE; 1.
DR   Pfam; PF00248; Aldo_ket_red; 1.
DR   SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
PE   4: Predicted;
FT   DOMAIN          16..315
FT                   /note="NADP-dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF00248"
SQ   SEQUENCE   327 AA;  35034 MW;  18457B739E0599EE CRC64;
     MESREFSKLG RSVSVVGLGT WQLGADWGDV EEKDAHAVLE AAADSGVTFF DTADVYGDGR
     SEQTIAAFLR AHPGSGITVA TKMGRRADQL PENYVLDNFR AWNDRSRRNL GVDRLDLVQL
     HCPPTPVYSS DEVYDALDTL VAEDRVAGYG VSVETCAEAL TAIARPGIAS VQIILNPFRM
     KPLAEVLPAA RAAGVGIIAR VPLASGLLSG KYTEDTTFAA NDHRTFNRHG EAFDQGETFA
     GVDFATGVAA AREFAALAPE GATPAQTALR WIVQQPGVTT VIPGARNTEQ ARANSAAGEL
     PPLAEDKLAA IRDLYEREIA PQVADRW
//