ID B5LXY1_GOSHI Unreviewed; 389 AA.
AC B5LXY1;
DT 14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2008, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Chalcone synthase {ECO:0000313|EMBL:ACH56521.1, ECO:0000313|RefSeq:XP_016699436.1};
GN Name=CHS5 {ECO:0000313|EMBL:AEO96988.1};
GN Synonyms=LOC107914895 {ECO:0000313|RefSeq:XP_016699436.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|EMBL:ACH56521.1};
RN [1] {ECO:0000313|EMBL:ACH56521.1}
RP NUCLEOTIDE SEQUENCE.
RA Yang H.-N., Li Y.-J., Sun J.;
RT "Cloning and expression analysis of pigment biosynthesis genes in colored
RT cotton fiber.";
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AEO96988.1}
RP NUCLEOTIDE SEQUENCE.
RA Li X.-B.;
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [4] {ECO:0000313|RefSeq:XP_016699436.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016699436.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC ECO:0000256|RuleBase:RU003633}.
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DR EMBL; EU921263; ACH56521.1; -; mRNA.
DR EMBL; JF795275; AEO96988.1; -; mRNA.
DR RefSeq; NP_001314048.1; NM_001327119.1.
DR RefSeq; XP_016699436.1; XM_016843947.1.
DR STRING; 3635.B5LXY1; -.
DR PaxDb; 3635-B5LXY1; -.
DR GeneID; 107914895; -.
DR KEGG; ghi:107914895; -.
DR OMA; TWVCHPG; -.
DR OrthoDB; 883077at2759; -.
DR Proteomes; UP000189702; Chromosome 22.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IBA:GO_Central.
DR GO; GO:0030639; P:polyketide biosynthetic process; IBA:GO_Central.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR018088; Chalcone/stilbene_synthase_AS.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877:SF14; CHALCONE SYNTHASE; 1.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00441; CHALCONE_SYNTH; 1.
PE 2: Evidence at transcript level;
KW Acyltransferase {ECO:0000256|RuleBase:RU003633};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Transferase {ECO:0000256|RuleBase:RU003633}.
FT DOMAIN 5..228
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 238..387
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 164
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 389 AA; 42668 MW; 89B809578AB23B34 CRC64;
MVTVEEVRKA QRAQGPATVL AIGTSTPPNC VDQSTYPDYY FRITNSEHKT ELKEKFKRMC
EKSMIKKRYM YLTEEILKEN PNVCEYMAPS LDARQDMVVV EVPKLGKEAA TKAIKEWGQP
KSKITHLVFC TTSGVDMPGA DYQLTKLLGL RPSVKRLMMY QQGCFAGGTV LRVAKDLAEN
NKGARVLVVC SEITAVTFRG PSDTHLDSLV GQALFGDGAA AVIIGADPMP EIEKPMFEIV
SVAQTILPDS DGAIDGHLRE VGLTFHLLKD VPGLISKNIE KSLVEAFQPL GISDWNSLFW
IAHPGGPAIL DQVEAKLALK PEKLRATRHV LSEYGNMSSA CVLFILDEMR KKSREDGLQT
TGEGLEWGVL FGFGPGLTVE TVVLHSVAA
//
