ID B5RCX5_SALG2 Unreviewed; 737 AA.
AC B5RCX5;
DT 04-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 04-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=Anti-FlhC(2)FlhD(4) factor YdiV {ECO:0000256|ARBA:ARBA00018009};
GN OrderedLocusNames=SG2535 {ECO:0000313|EMBL:CAR38361.1};
OS Salmonella gallinarum (strain 287/91 / NCTC 13346).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=550538 {ECO:0000313|EMBL:CAR38361.1, ECO:0000313|Proteomes:UP000008321};
RN [1] {ECO:0000313|EMBL:CAR38361.1, ECO:0000313|Proteomes:UP000008321}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=287/91 / NCTC 13346 {ECO:0000313|Proteomes:UP000008321};
RX PubMed=18583645; DOI=10.1101/gr.077404.108;
RA Thomson N.R., Clayton D.J., Windhorst D., Vernikos G., Davidson S.,
RA Churcher C., Quail M.A., Stevens M., Jones M.A., Watson M., Barron A.,
RA Layton A., Pickard D., Kingsley R.A., Bignell A., Clark L., Harris B.,
RA Ormond D., Abdellah Z., Brooks K., Cherevach I., Chillingworth T.,
RA Woodward J., Norberczak H., Lord A., Arrowsmith C., Jagels K., Moule S.,
RA Mungall K., Sanders M., Whitehead S., Chabalgoity J.A., Maskell D.,
RA Humphrey T., Roberts M., Barrow P.A., Dougan G., Parkhill J.;
RT "Comparative genome analysis of Salmonella enteritidis PT4 and Salmonella
RT gallinarum 287/91 provides insights into evolutionary and host adaptation
RT pathways.";
RL Genome Res. 18:1624-1637(2008).
CC -!- SUBUNIT: Interacts with FlhD in the FlhC(2)FlhD(4) heterohexamer,
CC inhibiting its ability to activate transcription.
CC {ECO:0000256|ARBA:ARBA00011576}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the YdiV family.
CC {ECO:0000256|ARBA:ARBA00010927}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AM933173; CAR38361.1; -; Genomic_DNA.
DR RefSeq; WP_000773641.1; NC_011274.1.
DR AlphaFoldDB; B5RCX5; -.
DR KEGG; seg:SG2535; -.
DR HOGENOM; CLU_023566_2_0_6; -.
DR Proteomes; UP000008321; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR007895; MASE1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF05231; MASE1; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR PROSITE; PS50883; EAL; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT TRANSMEM 15..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..235
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 493..737
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 737 AA; 84217 MW; F85178DAA5C01CAD CRC64;
MKLNKTYINI RDKWWGLPLI LPSILLPVLS SANTYALTST GNVVLFYLPL AFMLSLMLFF
GWAALPGIVL AIFWRRYPQT GLYETLSVTM HFIITIVLSW GGYRVFSPRR NNVSHGDAHL
LFQRIFWQVF CSATLFLVIY QFAAFVGMYE SKASLMGVMP FNINTLINYQ ALLVGNLVGV
PLCYFIIRTL RNPLHLRGYY QQLKLQIDSK ATKKEIVIWL AVLTTLMFIL CMPLTDNSSI
FSTNYTLSLL LPVMLWGAMR YGYKFISIIW AVVLITSIHY YQCYMPWYSG YDTQLAITSS
SYLVFSFIVN YMSVLATRQR VVSGRARRLA YLDPVVHLPN LRALNRALQN APWSTICFLH
VPGLELLGKN YGVMLRIQYK QKLSHWITPM LASNECVYQM SGHDLVLRLN TEAHQQRIEA
LDKHIKQFRF IWDGLPLQPP VGVSYCCVRS PVSHLYLLLG ELSTSSDLSL TTNAPEDLQR
RGAMHLQRDL KGRIAMMNRL QQALEHDHFF LMAQPIFGVR GDVYHEILLR LRDDNGDVIN
PDNFLPVAHE FGLSSAIDLW VIENTLRFMA ASREYMPAHR FAINLSPTSV CRARFPAEVK
QLLTQYQVEP WQLVFEVTES NSLTNAEQAQ LTLGQLQQFG CQIAIDDFGT GYASYARLKN
VDADILKIDG SFIRNIVSNS LDYQIVASIC HLARMKNMQV VAEYVESEEI RSVVLSLGID
YLQGYLIGEP QLLSEIQ
//
