ID B5RM08_BORDL Unreviewed; 418 AA.
AC B5RM08;
DT 04-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 04-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=RNA polymerase sigma-54 factor {ECO:0000313|EMBL:ACH93394.1};
GN Name=ntrA {ECO:0000313|EMBL:ACH93394.1};
GN OrderedLocusNames=BDU_449 {ECO:0000313|EMBL:ACH93394.1};
OS Borrelia duttonii (strain Ly).
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Borreliaceae;
OC Borrelia.
OX NCBI_TaxID=412419 {ECO:0000313|EMBL:ACH93394.1, ECO:0000313|Proteomes:UP000000611};
RN [1] {ECO:0000313|EMBL:ACH93394.1, ECO:0000313|Proteomes:UP000000611}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ly {ECO:0000313|EMBL:ACH93394.1,
RC ECO:0000313|Proteomes:UP000000611};
RX PubMed=18787695; DOI=10.1371/journal.pgen.1000185;
RA Lescot M., Audic S., Robert C., Nguyen T.T., Blanc G., Cutler S.J.,
RA Wincker P., Couloux A., Claverie J.-M., Raoult D., Drancourt M.;
RT "The genome of Borrelia recurrentis, the agent of deadly louse-borne
RT relapsing fever, is a degraded subset of tick-borne Borrelia duttonii.";
RL PLoS Genet. 4:E1000185-E1000185(2008).
CC -!- SIMILARITY: Belongs to the sigma-54 factor family.
CC {ECO:0000256|ARBA:ARBA00008798}.
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DR EMBL; CP000976; ACH93394.1; -; Genomic_DNA.
DR AlphaFoldDB; B5RM08; -.
DR STRING; 412419.BDU_449; -.
DR KEGG; bdu:BDU_449; -.
DR eggNOG; COG1508; Bacteria.
DR HOGENOM; CLU_020569_1_0_12; -.
DR OrthoDB; 9814402at2; -.
DR Proteomes; UP000000611; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001216; F:DNA-binding transcription activator activity; IEA:InterPro.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.10.1330; RNA polymerase sigma-54 factor, core-binding domain; 1.
DR InterPro; IPR000394; RNA_pol_sigma_54.
DR InterPro; IPR007046; RNA_pol_sigma_54_core-bd.
DR InterPro; IPR007634; RNA_pol_sigma_54_DNA-bd.
DR InterPro; IPR038709; RpoN_core-bd_sf.
DR NCBIfam; TIGR02395; rpoN_sigma; 1.
DR PANTHER; PTHR32248; RNA POLYMERASE SIGMA-54 FACTOR; 1.
DR PANTHER; PTHR32248:SF4; RNA POLYMERASE SIGMA-54 FACTOR; 1.
DR Pfam; PF04963; Sigma54_CBD; 1.
DR Pfam; PF04552; Sigma54_DBD; 1.
DR PIRSF; PIRSF000774; RpoN; 1.
DR PRINTS; PR00045; SIGMA54FCT.
DR PROSITE; PS00718; SIGMA54_2; 1.
DR PROSITE; PS50044; SIGMA54_3; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Sigma factor {ECO:0000256|ARBA:ARBA00023082};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 84..262
FT /note="RNA polymerase sigma factor 54 core-binding"
FT /evidence="ECO:0000259|Pfam:PF04963"
FT DOMAIN 270..410
FT /note="RNA polymerase sigma factor 54 DNA-binding"
FT /evidence="ECO:0000259|Pfam:PF04552"
FT COILED 176..210
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 418 AA; 48916 MW; 5B173FC627162EDD CRC64;
MLKQNLKLTH KLQLTQINTI KMLSLDKQEL IQIISDELDN NEYIKVDSNK IFFESLKTYK
FKKFFYKENE NNKTQYEIAL AKTSPKISLK EHLLLQLRIQ RLNEEEINIG EIIINNLNRK
GLYIINPYDF FNKEEWPQVT KMIKLIQQFD PIGICVPNII ESLILQAKYH NLDTNIIKIL
QKADLLTNTK EKLQKELNIS TQDLNDAINT MKLKLNPNPT FEFKDKDDTN DYIEPDIIVI
NKGNKLKIKI KEVSIFKTEI NKQEVKDLCK YKQAKWLIEA LRYRDETLAK IGIAIYTLQK
EFLKRGFKRL RPMNLDDIST RINLSKSTIS RAIKNKYLKF DWGTIAIRKL FNSIGGAKTN
EFSKLSIKII IKGILAQNKN MVDSQISDIL KSKGITISRR TVNKYRNELK CEGEIYGT
//
