ID   B5VJ17_YEAS6            Unreviewed;       665 AA.
AC   B5VJ17;
DT   25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT   25-NOV-2008, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   SubName: Full=YGR070Wp-like protein {ECO:0000313|EMBL:EDZ72078.1};
GN   ORFNames=AWRI1631_72960 {ECO:0000313|EMBL:EDZ72078.1};
OS   Saccharomyces cerevisiae (strain AWRI1631) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=545124 {ECO:0000313|EMBL:EDZ72078.1, ECO:0000313|Proteomes:UP000008988};
RN   [1] {ECO:0000313|EMBL:EDZ72078.1, ECO:0000313|Proteomes:UP000008988}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AWRI1631 {ECO:0000313|EMBL:EDZ72078.1,
RC   ECO:0000313|Proteomes:UP000008988};
RX   PubMed=18778279; DOI=10.1111/j.1567-1364.2008.00434.x;
RA   Borneman A.R., Forgan A.H., Pretorius I.S., Chambers P.J.;
RT   "Comparative genome analysis of a Saccharomyces cerevisiae wine strain.";
RL   FEMS Yeast Res. 8:1185-1195(2008).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EDZ72078.1}.
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DR   EMBL; ABSV01000936; EDZ72078.1; -; Genomic_DNA.
DR   AlphaFoldDB; B5VJ17; -.
DR   Proteomes; UP000008988; Unassembled WGS sequence.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   CDD; cd00160; RhoGEF; 1.
DR   Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR001180; CNH_dom.
DR   InterPro; IPR035899; DBL_dom_sf.
DR   InterPro; IPR000219; DH-domain.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR041675; PH_5.
DR   PANTHER; PTHR46572; RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED; 1.
DR   PANTHER; PTHR46572:SF2; RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED; 1.
DR   Pfam; PF00780; CNH; 1.
DR   Pfam; PF15405; PH_5; 1.
DR   Pfam; PF00621; RhoGEF; 1.
DR   SMART; SM00036; CNH; 1.
DR   SMART; SM00325; RhoGEF; 1.
DR   SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50219; CNH; 1.
DR   PROSITE; PS50010; DH_2; 1.
PE   4: Predicted;
FT   DOMAIN          1..161
FT                   /note="DH"
FT                   /evidence="ECO:0000259|PROSITE:PS50010"
FT   DOMAIN          352..647
FT                   /note="CNH"
FT                   /evidence="ECO:0000259|PROSITE:PS50219"
SQ   SEQUENCE   665 AA;  76799 MW;  A0341DFB07F39BCF CRC64;
     MKKLLETNII PSDVRINFVK HVFAHINEIY SVNREFLKAL AQRQSLSPIC PGIADIFLQY
     LPFFDPFLSY IASRPYAKYL IETQRSVNPN FARFDDEVSN SSLRHGIDSF LSQGVSRPGR
     YSLLVREIIH FSDPVTDKDD LQMLMKVQDL LKDLMKRIDR ASGAAQDRYD VKVLKQKILF
     KNEYVNLGLN NEKRKIKHEG LLSRKDVNKT DASFSGDIQF YLLDNMLLFL KSKAVNKWHQ
     HTVFQRPIPL PLLFICPAED MPPIKRYVTE NPNCSAGVLL PQYQTSNPKN AIVFAYYGTK
     QQYQVTLYAP QPAGLQTLIE KVKQEQKRLL DETKHITFKQ MVGQFFHSYI NTNRVNDVLI
     CHAGKILLVA TNMGLFVLNY ATSINQKPVH LLHKISISQI SVLEEYKVMI LLIDKKLYGC
     PLDVIDDAEN ADFLFRKNSK VLFKYVAMFK DGFCNGKRII MIAHHFLHTV QLLIVNPLIF
     DFNSGNFKKN LKAGLVDFSV DSEPLSFSFL ENKICIGCKK NIKILNVPEV CDKNGFKMRE
     LLNLHDNKVL ANMYKETFKV VSMFPIKNST FACFPELCFF LNKQGKREET KGCFHWEGEP
     EQFACSYPYI VAINSNFIEI RHIENGELVR CVLGNKIRML KSYAKKILYC YEDPQGFEII
     ELLNF
//