ID B5XAC8_SALSA Unreviewed; 299 AA.
AC B5XAC8;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Cyclin-G1 {ECO:0000256|ARBA:ARBA00019866};
GN Name=CCNG1 {ECO:0000313|EMBL:ACI67798.1};
GN Synonyms=LOC106604232 {ECO:0000313|RefSeq:XP_014054170.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|EMBL:ACI67798.1};
RN [1] {ECO:0000313|EMBL:ACI67798.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Thymus {ECO:0000313|EMBL:ACI67798.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RA Leong J., von Schalburg K., Cooper G., Moore R., Holt R., Davidson W.S.,
RA Koop B.F.;
RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACI67798.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Thymus {ECO:0000313|EMBL:ACI67798.1};
RX PubMed=20433749; DOI=10.1186/1471-2164-11-279;
RA Leong J.S., Jantzen S.G., von Schalburg K.R., Cooper G.A., Messmer A.M.,
RA Liao N.Y., Munro S., Moore R., Holt R.A., Jones S.J., Davidson W.S.,
RA Koop B.F.;
RT "Salmo salar and Esox lucius full-length cDNA sequences reveal changes in
RT evolutionary pressures on a post-tetraploidization genome.";
RL BMC Genomics 11:279-279(2010).
RN [3] {ECO:0000313|EMBL:ACI67798.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Thymus {ECO:0000313|EMBL:ACI67798.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|RefSeq:XP_014054170.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014054170.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May play a role in growth regulation. Is associated with G2/M
CC phase arrest in response to DNA damage. May be an intermediate by which
CC p53 mediates its role as an inhibitor of cellular proliferation.
CC {ECO:0000256|ARBA:ARBA00025528}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin G subfamily.
CC {ECO:0000256|ARBA:ARBA00010389}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BT047997; ACI67798.1; -; mRNA.
DR RefSeq; XP_014054170.1; XM_014198695.1.
DR GeneID; 106604232; -.
DR KEGG; sasa:106604232; -.
DR OrthoDB; 3032827at2759; -.
DR Proteomes; UP000087266; Chromosome ssa05.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR039361; Cyclin.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10177:SF59; CYCLIN-G1; 1.
DR PANTHER; PTHR10177; CYCLINS; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR SMART; SM00385; CYCLIN; 1.
DR SUPFAM; SSF47954; Cyclin-like; 1.
PE 2: Evidence at transcript level;
KW Cyclin {ECO:0000256|ARBA:ARBA00023127, ECO:0000256|RuleBase:RU000383};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 57..143
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
SQ SEQUENCE 299 AA; 34504 MW; 4FD1A9074F720795 CRC64;
MLPTVTGPGA LPFAVQLKAL TDQEFRYQPK LSGLRIIEMA HDNGLRMTAR LREYEVKDLL
SLTRFFGFSA ETFSLAINLL DRFLAVMKIQ PKHLSCVGLS CFYIAVKTSE EEKNVAMANE
LIRISQNRFT VSDMMRMEKI ILEKLYWKVK APTALHFLRL FYSCIQDTLE DDCKEILNIE
RLEAQLKACH CSFTFSKVKP SLLALSLLAL ELQEQHDHEH VDKLLNAFQS LQQQLTVREG
DLVIVTELVM KCLIDYSTTR VSRPNSQRLR WILSGRTQRT LKHSYYKIAH MPTIPESAY
//
