ID B5Y383_KLEP3 Unreviewed; 442 AA.
AC B5Y383;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=Poly-beta-1,6-N-acetyl-D-glucosamine synthase {ECO:0000256|RuleBase:RU364028};
DE Short=Poly-beta-1,6-GlcNAc synthase {ECO:0000256|RuleBase:RU364028};
DE EC=2.4.1.- {ECO:0000256|RuleBase:RU364028};
GN Name=pgaC {ECO:0000313|EMBL:ACI10823.1};
GN OrderedLocusNames=KPK_5153 {ECO:0000313|EMBL:ACI10823.1};
OS Klebsiella pneumoniae (strain 342).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=507522 {ECO:0000313|EMBL:ACI10823.1, ECO:0000313|Proteomes:UP000001734};
RN [1] {ECO:0000313|EMBL:ACI10823.1, ECO:0000313|Proteomes:UP000001734}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=342 {ECO:0000313|EMBL:ACI10823.1,
RC ECO:0000313|Proteomes:UP000001734};
RX PubMed=18654632; DOI=10.1371/journal.pgen.1000141;
RA Fouts D.E., Tyler H.L., DeBoy R.T., Daugherty S., Ren Q., Badger J.H.,
RA Durkin A.S., Huot H., Shrivastava S., Kothari S., Dodson R.J., Mohamoud Y.,
RA Khouri H., Roesch L.F., Krogfelt K.A., Struve C., Triplett E.W.,
RA Methe B.A.;
RT "Complete genome sequence of the N2-fixing broad host range endophyte
RT Klebsiella pneumoniae 342 and virulence predictions verified in mice.";
RL PLoS Genet. 4:E1000141-E1000141(2008).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364028};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364028}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family.
CC {ECO:0000256|RuleBase:RU364028}.
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DR EMBL; CP000964; ACI10823.1; -; Genomic_DNA.
DR AlphaFoldDB; B5Y383; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR KEGG; kpe:KPK_5153; -.
DR HOGENOM; CLU_023978_0_1_6; -.
DR PHI-base; PHI:3448; -.
DR Proteomes; UP000001734; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008375; F:acetylglucosaminyltransferase activity; IEA:InterPro.
DR GO; GO:0043708; P:cell adhesion involved in biofilm formation; IEA:InterPro.
DR CDD; cd06423; CESA_like; 1.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR023853; PGA_PgaC/IcaA.
DR NCBIfam; TIGR03937; PgaC_IcaA; 1.
DR PANTHER; PTHR43630; POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE SYNTHASE; 1.
DR PANTHER; PTHR43630:SF1; POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE SYNTHASE; 1.
DR Pfam; PF13641; Glyco_tranf_2_3; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU364028};
KW Glycosyltransferase {ECO:0000256|RuleBase:RU364028,
KW ECO:0000313|EMBL:ACI10823.1}; Membrane {ECO:0000256|RuleBase:RU364028};
KW Transferase {ECO:0000256|RuleBase:RU364028, ECO:0000313|EMBL:ACI10823.1};
KW Transmembrane {ECO:0000256|RuleBase:RU364028};
KW Transmembrane helix {ECO:0000256|RuleBase:RU364028}.
FT TRANSMEM 33..54
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364028"
FT TRANSMEM 319..345
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364028"
FT TRANSMEM 365..384
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364028"
FT TRANSMEM 396..418
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364028"
SQ SEQUENCE 442 AA; 50406 MW; C6828A959E01605A CRC64;
MTDRIIALCI LCLVFGLPLG VAAVFTGELI LDFVFFWPLF MSVLWITGGL YFWFQLERHW
PWGEDTPPPT LPGNPLISIL IPCFNEEKNA RETISAALAQ RYANLEVIAI NDGSSDNTAQ
VLQQLAQEEP RLRVIHLAAN QGKAVALKAG AAAARGDLLV CIDGDALLDR DTAAWLVAPL
IHYPHVGAVT GNPRIRTRST LIGRIQVGEF SSIIGLIKRT QRIYGRVFTV SGVIAAFRRQ
ALADVGYWSP DMITEDIDIS WKLQLRHWDI FFEPRALCWI LMPETLKGLW KQRLRWAQGG
AEVFLVNLRR LFHWEHHRMW PLFLEYACST LWAFAYAVTI LLFILSRLMP LPDNLAVHSL
FPPEFTGMLL GVMCLLQFVA SLYIERRYEK KVAKSLFWVI WFPMVYWMIG LLTTLVAFPK
VMVKRQRSRA RWVSPDRGKG SL
//
