ID B5Z9N0_HELPG Unreviewed; 675 AA.
AC B5Z9N0;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Methyl-accepting chemotaxis transmembrane sensory protein {ECO:0000313|EMBL:ACI26860.1};
GN Name=tlpA {ECO:0000313|EMBL:ACI26860.1};
GN OrderedLocusNames=HPG27_91 {ECO:0000313|EMBL:ACI26860.1};
OS Helicobacter pylori (strain G27).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=563041 {ECO:0000313|EMBL:ACI26860.1, ECO:0000313|Proteomes:UP000001735};
RN [1] {ECO:0000313|EMBL:ACI26860.1, ECO:0000313|Proteomes:UP000001735}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G27 {ECO:0000313|EMBL:ACI26860.1,
RC ECO:0000313|Proteomes:UP000001735};
RX PubMed=18952803; DOI=10.1128/JB.01416-08;
RA Baltrus D.A., Amieva M.R., Covacci A., Lowe T.M., Merrell D.S.,
RA Ottemann K.M., Stein M., Salama N.R., Guillemin K.;
RT "The complete genome sequence of Helicobacter pylori strain G27.";
RL J. Bacteriol. 191:447-448(2009).
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001173; ACI26860.1; -; Genomic_DNA.
DR RefSeq; WP_000033611.1; NC_011333.1.
DR AlphaFoldDB; B5Z9N0; -.
DR KEGG; hpg:HPG27_91; -.
DR HOGENOM; CLU_000445_107_30_7; -.
DR Proteomes; UP000001735; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR004089; MCPsignal_dom.
DR PANTHER; PTHR32089:SF112; HEME-BASED AEROTACTIC TRANSDUCER HEMAT; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284};
KW Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|EMBL:ACI26860.1};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..327
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 475..675
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
FT COILED 586..641
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 675 AA; 74832 MW; FC57E8F4B16D1456 CRC64;
MSKGLSIGNK IILWVALIVI VCVSILGVSL NSRVKEILKE NTLRSMQDSL HFKVKEVQGV
LENTYTSMGI VKEMLPKDTK REIKIRLLKN FILANSHVAG VSMFFKNRED LRLTLLRDND
TIKLMENPSL GNSPLAQKAM KNKEISKSLP YYRKMPNGAE VYGVDILLPL LNENAQEVVG
ALMVFISIDS FSNEITKNRS DLFLIGVKGK VLLSANKSLQ DKSIAEIYKS VPKATNEVMA
ILENGSKATL EYLDPFSHKE NFLAVETFKM LGKTESKDNL NWMIALIIEK DKVYEQVGSV
RFVVIIASAI MVLALIIAIT LLMRAIVSSR LEVVSSTLSH FFKLLNNQAH SSDIKLIEAK
SNDELGHMQT AINKNILQTQ KTMQEDKQAV QDTIKVVSDV KAGNFAVRIT AEPASPDLKE
LRDALNGIMD YLQESVGTHM PSIFKIFESY SGLDFRGRIQ NASGRVELVT NALGQEIQKM
LETSSNFAKD LANDSANLKE CVQNLEKASN SQHKSLMETS KTIENITTSI QGVSSQSEAM
IEQGQDIKSI VEIIRDIADQ TNLLALNAAI EAARAGEHGR GFAVVADEVR KLAERTQKSL
SEIEANINIL VQSISDTSES IKNQVKEVEE INASIEALRS VIEGNLKIAS DSLEISQEID
KVSNDILEDV NKKQF
//
