ID B6A3M9_RHILW Unreviewed; 902 AA.
AC B6A3M9;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 27-MAR-2024, entry version 109.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=Rleg2_5839 {ECO:0000313|EMBL:ACI59012.1};
OS Rhizobium leguminosarum bv. trifolii (strain WSM2304).
OG Plasmid pRLG202 {ECO:0000313|EMBL:ACI59012.1,
OG ECO:0000313|Proteomes:UP000008330}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX NCBI_TaxID=395492 {ECO:0000313|EMBL:ACI59012.1, ECO:0000313|Proteomes:UP000008330};
RN [1] {ECO:0000313|EMBL:ACI59012.1, ECO:0000313|Proteomes:UP000008330}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSM2304 {ECO:0000313|EMBL:ACI59012.1,
RC ECO:0000313|Proteomes:UP000008330};
RC PLASMID=pRLG202 {ECO:0000313|EMBL:ACI59012.1};
RX PubMed=21304679; DOI=10.4056/sigs.44642;
RA Reeve W., O'Hara G., Chain P., Ardley J., Brau L., Nandesena K., Tiwari R.,
RA Malfatti S., Kiss H., Lapidus A., Copeland A., Nolan M., Land M.,
RA Ivanova N., Mavromatis K., Markowitz V., Kyrpides N., Melino V., Denton M.,
RA Yates R., Howieson J.;
RT "Complete genome sequence of Rhizobium leguminosarum bv trifolii strain
RT WSM2304, an effective microsymbiont of the South American clover Trifolium
RT polymorphum.";
RL Stand. Genomic Sci. 2:66-76(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP001193; ACI59012.1; -; Genomic_DNA.
DR RefSeq; WP_012555210.1; NC_011366.1.
DR AlphaFoldDB; B6A3M9; -.
DR KEGG; rlt:Rleg2_5839; -.
DR HOGENOM; CLU_000445_113_1_5; -.
DR Proteomes; UP000008330; Plasmid pRLG202.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01987; USP_OKCHK; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF13492; GAF_3; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF02702; KdpD; 1.
DR Pfam; PF00582; Usp; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ion channel {ECO:0000313|EMBL:ACI59012.1};
KW Ion transport {ECO:0000313|EMBL:ACI59012.1};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ACI59012.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Plasmid {ECO:0000313|EMBL:ACI59012.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000313|EMBL:ACI59012.1};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 402..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..445
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 451..469
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 481..501
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 676..893
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 902 AA; 98542 MW; 4287F7067465C8AC CRC64;
MPDDNRDQAG RPSPDALLEK ARAETRGRLK IFLGAAPGVG KTYEMLLSGR AKIADGFDVV
IGVVETHGRK ETEALLAGFE IIPRVEIDYK GRLLEEMDLD GILARRPDLV LVDELAHTNA
EGSRHPKRYL DVKELLDRGI DVYSTLNIQH VESLNDVVSQ ITRIRVRETV PDSIIDLADD
VEIIDLTPDD LIKRLHDGKV YMPRTAERAL TNYFTPGNLT ALRELALRKT AQRVDDQLLT
HMQAHAISGP WAAGERVLVS VDHHPRSASL VRYASRMASR LRAPWAAVYV ETNRSINLSE
AERDTIASTL RLAEQLGGEA ITIPGREVAD ELVRHASANN VTHIVIGAPK KPTWRDWWGR
SITDELIRKT GEISVHVISG TEKDGTTARG VKAAATAPQL DLRAYLLATV YVAIALGVSI
VLDQVLDVRN LALVFLMAVL TSAVLHGLRP ALYSCILSAL SFNFFFLPPR YTLTISDPES
VLALFFFLGV AIIASNLTAT VQRQAAAARQ RARTTEDLYL FSKKLAGTGT LDDVLWATAF
QLASMLKVRV VLLLPEEGSI AVKAGYPPDD TLDDADIAAA RWAWEHNHAA GRGADTLPGA
KRLYVPLRTG RTAVGVIGLD SDRRDGPLLT PEQQRLLDAL ADQAALAIER VQLVADVDRA
RLAAEADRLR SALLTSISHD LKTPLAAILG AAGTLRDYFA SMPEEDRSDL LSTVVDESER
LNRFIANLLD MTKIESGAME PNSALHYAGD IVGSALRRAA KMLERHRTEM SIPADLPMVR
VDPVLFEQVI FNLLDNAAKY APEGSIIHIG GWADADNVVL QVSDEGPGIP PADLTRVFDT
FYRVRKGDQV RAGTGLGLSI CRGFIEAMGG TIAAGNRTGR SGAVFTIRLP KPNDIPKLDE
LK
//
