ID B6D504_ACTNA Unreviewed; 359 AA.
AC B6D504;
DT 25-NOV-2008, integrated into UniProtKB/TrEMBL.
DT 25-NOV-2008, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
DE Flags: Fragment;
GN Name=nanH {ECO:0000313|EMBL:ACH92833.1};
OS Actinomyces naeslundii.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=1655 {ECO:0000313|EMBL:ACH92833.1};
RN [1] {ECO:0000313|EMBL:ACH92833.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=G127B {ECO:0000313|EMBL:ACH92833.1};
RA Do T., Henssge U., Gilbert S.C., Clark D., Beighton D.;
RT "Evidence for recombination between a sialidase (nanH) of Actinomyces
RT naeslundii and Actinomyces oris, previously named 'Actinomyces naeslundii
RT genospecies 1 and 2'.";
RL FEMS Microbiol. Lett. 288:156-162(2008).
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DR EMBL; EU805611; ACH92833.1; -; Genomic_DNA.
DR AlphaFoldDB; B6D504; -.
DR CAZy; GH33; Glycoside Hydrolase Family 33.
DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR026856; Sialidase_fam.
DR InterPro; IPR036278; Sialidase_sf.
DR PANTHER; PTHR10628; SIALIDASE; 1.
DR PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR Pfam; PF13088; BNR_2; 1.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 4: Predicted;
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 75..358
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13088"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 50..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..35
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..92
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACH92833.1"
FT NON_TER 359
FT /evidence="ECO:0000313|EMBL:ACH92833.1"
SQ SEQUENCE 359 AA; 38369 MW; 39E345DC8C4081B1 CRC64;
VGQHPQAEPA PAPDASTELP ASMSEAQHLA GNTATDNYRI PAITTAPNGD LLVSYDERPK
DNGNGGSDAP NPNHIVQRRS TDGGKTWSAP TYIHQGTETG KKVGYSDPSY VVDHQTGTIF
NFHVKSYDQG WGGSKAGTDP ENRSIIQAEV STSTDNGWTW THRTITADIT KDNPWTARFA
ASGQGIQIQH GAHAGRLVQQ YTIRTADGTV QAVSVYSDDH GKTWQAGTPT GTGMDENKVV
ELSDGSLMLN SRASDGSGFR KVARSTDGGQ TWSEPASDKN LPDSVDNAQI IRAFPNAAPS
DPRAKVLLLS HSPNPKPWSR DRGTISMSCD DGASWATSKV FNENFVGYMT IAVQSDGSI
//
