ID   B6H126_PENRW            Unreviewed;       918 AA.
AC   B6H126;
DT   16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   SubName: Full=Pc12g14550 protein {ECO:0000313|EMBL:CAP81082.1};
GN   ORFNames=Pc12g14550 {ECO:0000313|EMBL:CAP81082.1}, PCH_Pc12g14550
GN   {ECO:0000313|EMBL:CAP81082.1};
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS   54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP81082.1, ECO:0000313|Proteomes:UP000000724};
RN   [1] {ECO:0000313|EMBL:CAP81082.1, ECO:0000313|Proteomes:UP000000724}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC   {ECO:0000313|Proteomes:UP000000724};
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA   van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA   Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR   EMBL; AM920427; CAP81082.1; -; Genomic_DNA.
DR   RefSeq; XP_002558260.1; XM_002558214.1.
DR   AlphaFoldDB; B6H126; -.
DR   STRING; 500485.B6H126; -.
DR   CAZy; GH55; Glycoside Hydrolase Family 55.
DR   GeneID; 8308275; -.
DR   KEGG; pcs:Pc12g14550; -.
DR   VEuPathDB; FungiDB:PCH_Pc12g14550; -.
DR   eggNOG; ENOG502SH8Z; Eukaryota.
DR   HOGENOM; CLU_002540_1_0_1; -.
DR   OMA; AYIENFW; -.
DR   OrthoDB; 3714838at2759; -.
DR   BioCyc; PCHR:PC12G14550-MONOMER; -.
DR   Proteomes; UP000000724; Contig Pc00c12.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0004650; F:polygalacturonase activity; IEA:InterPro.
DR   Gene3D; 2.160.20.10; Single-stranded right-handed beta-helix, Pectin lyase-like; 2.
DR   InterPro; IPR024535; Pectate_lyase_SF_prot.
DR   InterPro; IPR012334; Pectin_lyas_fold.
DR   InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR   InterPro; IPR039279; QRT3-like.
DR   PANTHER; PTHR33928:SF2; PECTATE LYASE SUPERFAMILY PROTEIN DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR33928; POLYGALACTURONASE QRT3; 1.
DR   Pfam; PF12708; Pectate_lyase_3; 2.
DR   SUPFAM; SSF51126; Pectin lyase-like; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000724};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..918
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002843385"
FT   DOMAIN          211..429
FT                   /note="Pectate lyase superfamily protein"
FT                   /evidence="ECO:0000259|Pfam:PF12708"
FT   DOMAIN          547..608
FT                   /note="Pectate lyase superfamily protein"
FT                   /evidence="ECO:0000259|Pfam:PF12708"
FT   REGION          94..118
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          137..183
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        137..178
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   918 AA;  98242 MW;  D9F427D66B759750 CRC64;
     MRGFPFLASV AAVSTASGAI VPLNSVRASS SYVLSSTIIH SRPAYDYYDY PFDWALASSL
     AGLTGAPPTA TVHQHGTTTS PCTANTLSTA AEFTPKPVNA STGTPSQKAA SSSSKMMQPT
     WTAVNSNSAA PNTLATSVKT STPLPKTHTQ STRASVPTPS PMSQKDHSPA TKTCAAPTGK
     SPETYWLDEQ DHNQRGAGFA PYAKTSLYPV YRNVMDYSVV NDGSGNQTPK LQKAIDDDGA
     GGSRKGHGVT RYPALVYLPG GVYQLESTLN LTVGTIIVGN PLNPPIIKAA PGFRGDYLIM
     GYDSHNGNPE TSFATLVKNV IMDTTALSPD RHFTALQWGV AQGSGLTNVK IRMPKSSTGH
     TGIDINAGST IAVTDVHITG GAIGIKNSNQ QVNFKNIYFH SCRTAFSAAG GWTVLLQQAT
     FYSCGTGIDM TGNGLGSLVL LDSTSVNSGP VIRFYDSSHD SGNRNSQFLI QNLKHDTPNA
     IAVDAHGNVA LAATPYVDTW VWGTVVPETY QTGASWETKR PAALVVGDKY FTKAQPTYQD
     YSAADIVNVK TVSGHTVKGD GKTDDTEALN AILAQNADSC KVTYIPFGVY RVSNTIFVPV
     GTRMVGEAWS VISGYGDNFK DPNNPRPVVQ LGNPGDVGVI EIQEMRFSVG EPLPGAKIIE
     INAAGDKPGD VGLWNTMGMV GGTADTSISS ACTSQDPKDC MAAFMVMHLT KSSSAYIENF
     WGWTADHNID SESLLTIIST GRGILVESTK ATWLTGTGSE HHWLYNYNFH NAQNVFAGLL
     QTETPYMQGQ GEYRAAPEPW TAVAKYGDPD FSWCAADDQK CRTAIATNVD GGSNIALYNS
     AAWAFFDGYW NGLYNEPCNG NCQTNMMRVT NEPQNLVWYS ISTRMTDVMV LDGKSNPRQS
     DHRGGWEGII QVYGQFTA
//