ID   B6HB54_PENRW            Unreviewed;       888 AA.
AC   B6HB54;
DT   16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   SubName: Full=Pc18g02850 protein {ECO:0000313|EMBL:CAP94509.1};
GN   ORFNames=Pc18g02850 {ECO:0000313|EMBL:CAP94509.1}, PCH_Pc18g02850
GN   {ECO:0000313|EMBL:CAP94509.1};
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS   54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP94509.1, ECO:0000313|Proteomes:UP000000724};
RN   [1] {ECO:0000313|EMBL:CAP94509.1, ECO:0000313|Proteomes:UP000000724}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC   {ECO:0000313|Proteomes:UP000000724};
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA   van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA   Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
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DR   EMBL; AM920433; CAP94509.1; -; Genomic_DNA.
DR   RefSeq; XP_002562126.1; XM_002562080.1.
DR   AlphaFoldDB; B6HB54; -.
DR   GeneID; 8316314; -.
DR   KEGG; pcs:Pc18g02850; -.
DR   VEuPathDB; FungiDB:PCH_Pc18g02850; -.
DR   eggNOG; ENOG502SJFZ; Eukaryota.
DR   HOGENOM; CLU_016056_0_0_1; -.
DR   OMA; AWLLHSH; -.
DR   OrthoDB; 69264at2759; -.
DR   BioCyc; PCHR:PC18G02850-MONOMER; -.
DR   Proteomes; UP000000724; Contig Pc00c18.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR000917; Sulfatase_N.
DR   PANTHER; PTHR43751:SF3; N-ACETYLGALACTOSAMINE 6-SULFATASE (GALNS); 1.
DR   PANTHER; PTHR43751; SULFATASE; 1.
DR   Pfam; PF00884; Sulfatase; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000724};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        40..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        76..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        119..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          521..714
FT                   /note="Sulfatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00884"
FT   REGION          748..785
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        762..785
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   888 AA;  99110 MW;  908DDB3802E7E670 CRC64;
     MSIFALLPPL PPFLFSTLVV SGLASKALHI ALHIRSLPFL YFVLYSPTLI LRDVLVIIFV
     RVLLRFHAPD SRWQWLSTGL GGALSLITWG ASSIQFGFFM QTGAEVAWAA GGSFRSDPAA
     MKILLSGIST VSAAATVLGL IAWLLHSHLY NITGLGLQAI RDLCVGGYKA RYTLISAPSK
     SCMASIDLRT FRRVIPAVAI CVSLIFLELT RPAIPYDHLS GALPLTLLDA FQKKTATVEG
     CREPARPFPL SVTDDNGVSR PQFQPDSSLV EQWSRATWLP ENPPPGFSRW DLSPSDRAEK
     DNHYSFVCPG DEGAFYNPKN DPLMITNLGG EIYEPLQKAF KEHSIEVNHV VLLTLESGRK
     ELFPTQQGTP LFDGLLASHK KENIDEAIDR LVNMTPVAQQ LTGEYATDSK GNKLDLSYSP
     WQTPPQEGMG GLNVRGAVTG SSLTLKSILG SHCGVNPLPV DLLEESMLEI YQPCLPQIFD
     LFNQGKSESG KLPQNFSSES KSAALQNPWK SVFMQSITDD YDRQDVLNKN MGFKHKVAKS
     NLESPHAKHK AQGEEINYFG YAENEIRPYL LDLFEEAANN KTRMFLSHVT STTHHPWSTP
     DDFEREPYMS DQGNINHDLM NNYLNAARFV DIWLGEILNM LDQTGIANET LVVVVGDHGQ
     AFGEDNKDMT GTYENGHISN FRVPLVFHHP HMPRVDITAN ATALTIVPTI LDLLVQSNSL
     DEHDSEIASS LLPEYQGQSL LRPFLSSMEE PPHRRDHHHH HHRPPPDEQP EHEQDTQLEA
     RSHPENPAKR IVWNMGLINA GGSMLSVMAA DVPYRLILPL KDGFEYTFTH LGEDPGETHL
     TKAWTLKALL EEVKPKFGKE SADWLEDAEL VGKWWVSEQK RIWGYREA
//