ID   B6HH54_PENRW            Unreviewed;       757 AA.
AC   B6HH54;
DT   16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 1.
DT   27-MAR-2024, entry version 71.
DE   SubName: Full=Pc20g03840 protein {ECO:0000313|EMBL:CAP85713.1};
GN   ORFNames=Pc20g03840 {ECO:0000313|EMBL:CAP85713.1}, PCH_Pc20g03840
GN   {ECO:0000313|EMBL:CAP85713.1};
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS   54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP85713.1, ECO:0000313|Proteomes:UP000000724};
RN   [1] {ECO:0000313|EMBL:CAP85713.1, ECO:0000313|Proteomes:UP000000724}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC   {ECO:0000313|Proteomes:UP000000724};
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA   van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA   Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC       {ECO:0000256|ARBA:ARBA00005641}.
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DR   EMBL; AM920435; CAP85713.1; -; Genomic_DNA.
DR   RefSeq; XP_002562934.1; XM_002562888.1.
DR   AlphaFoldDB; B6HH54; -.
DR   CAZy; GH5; Glycoside Hydrolase Family 5.
DR   GeneID; 8309989; -.
DR   KEGG; pcs:Pc20g03840; -.
DR   VEuPathDB; FungiDB:PCH_Pc20g03840; -.
DR   eggNOG; ENOG502QPU8; Eukaryota.
DR   HOGENOM; CLU_009024_0_1_1; -.
DR   OMA; GWKRDPQ; -.
DR   OrthoDB; 69117at2759; -.
DR   BioCyc; PCHR:PC20G03840-MONOMER; -.
DR   Proteomes; UP000000724; Contig Pc00c20.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:1901136; P:carbohydrate derivative catabolic process; IEA:UniProt.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProt.
DR   GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProt.
DR   Gene3D; 3.20.20.80; Glycosidases; 2.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR041036; GH5_C.
DR   InterPro; IPR001547; Glyco_hydro_5.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR31308; -; 1.
DR   PANTHER; PTHR31308:SF5; ERGOSTERYL-BETA-GLUCOSIDASE; 1.
DR   Pfam; PF00150; Cellulase; 1.
DR   Pfam; PF18564; Glyco_hydro_5_C; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000724}.
FT   DOMAIN          70..129
FT                   /note="Glycoside hydrolase family 5"
FT                   /evidence="ECO:0000259|Pfam:PF00150"
FT   DOMAIN          636..725
FT                   /note="Glycoside hydrolase family 5 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18564"
FT   REGION          570..621
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        575..596
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        605..621
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   757 AA;  85620 MW;  30984E67F7240D27 CRC64;
     MAPLHLKVEG QTFRDPHNRE ITLRGINVAA DAKYPKTPDV PSYIAENFFD ADNVSFVERP
     FSLEDAHIHF KRLRKWGYNT IRYIFTWEAI EHAGPGVYDH EWVAYTIEVL RIAKQYDFWV
     FMDPHQDVWS RLSGGSGAPM WTLYAAGLNP RTFKDTEAAL VQNTYDIPAE FPKMIWSTNY
     TRLVCQTMFT LFWAGRDFAP KAIIDGMNIQ DYLQDHFINA CAFLARRIHE AGDLGEVIIG
     WESMNEPHRG LVGVQDISVI PPEQQLQLGT SPTAFQAMLT GSGKACEQTT WAFGNFGPYK
     TGTNLVDPAG VIAWLPADQS FNDNQYGWQR DPGWKLGECI WAQHGVWDPS TDVLLQKDYF
     SKKPTGEPLD YEKFTNSYFL DHYRAYKNAI RRIWPDAIMF CQPPVMEVPP DIKGTTDDDP
     NMVHAVHFYD GLTLLTKHWN RLYNVDVIGV LRGKYLTPAF ALKVGETAIR NCLRDQLKFL
     RDESRNYMGS HPVVFTEIGI PYDMDDKYAY KTGDYSSQTS AMDANHFALE GSTSNGFTLW
     VYVTQNDHEW GDQWNGEDLS IYSRDDLDLP AGSSTRPLDP NSPAFSESQS SGAEAEPNVG
     PRNLKGVLST PSISSERSQI PLRQQQGYRA AEAYLRPSPT YVSGKLDSHV FDLKNCVFTL
     SLTAKGATTA TAPTEIYLPD FHFPESNIVV TVSGGKWDID VQDIQGAKLQ RLRWWHAEGE
     QDIKIEGLKR KPGEFGNPGG QDVGYLEQCQ KGECVMM
//