ID B6IW57_RHOCS Unreviewed; 427 AA.
AC B6IW57;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Threonine dehydratase {ECO:0000313|EMBL:ACJ00531.1};
DE EC=4.3.1.19 {ECO:0000313|EMBL:ACJ00531.1};
GN Name=ilvA {ECO:0000313|EMBL:ACJ00531.1};
GN OrderedLocusNames=RC1_3167 {ECO:0000313|EMBL:ACJ00531.1};
OS Rhodospirillum centenum (strain ATCC 51521 / SW).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Rhodospirillaceae; Rhodospirillum.
OX NCBI_TaxID=414684 {ECO:0000313|EMBL:ACJ00531.1, ECO:0000313|Proteomes:UP000001591};
RN [1] {ECO:0000313|Proteomes:UP000001591}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51521 / SW {ECO:0000313|Proteomes:UP000001591};
RA Touchman J.W., Bauer C., Blankenship R.E.;
RT "Genome sequence of Rhodospirillum centenum.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACJ00531.1, ECO:0000313|Proteomes:UP000001591}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51521 / SW {ECO:0000313|Proteomes:UP000001591};
RX PubMed=20500872; DOI=10.1186/1471-2164-11-325;
RA Lu Y.K., Marden J., Han M., Swingley W.D., Mastrian S.D., Chowdhury S.R.,
RA Hao J., Helmy T., Kim S., Kurdoglu A.A., Matthies H.J., Rollo D.,
RA Stothard P., Blankenship R.E., Bauer C.E., Touchman J.W.;
RT "Metabolic flexibility revealed in the genome of the cyst-forming alpha-1
RT proteobacterium Rhodospirillum centenum.";
RL BMC Genomics 11:325-325(2010).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR EMBL; CP000613; ACJ00531.1; -; Genomic_DNA.
DR AlphaFoldDB; B6IW57; -.
DR STRING; 414684.RC1_3167; -.
DR KEGG; rce:RC1_3167; -.
DR eggNOG; COG1171; Bacteria.
DR HOGENOM; CLU_021152_4_1_5; -.
DR OrthoDB; 9811476at2; -.
DR Proteomes; UP000001591; Chromosome.
DR GO; GO:0003941; F:L-serine ammonia-lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0004794; F:L-threonine ammonia-lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0006567; P:threonine catabolic process; IEA:InterPro.
DR CDD; cd04886; ACT_ThrD-II-like; 1.
DR CDD; cd01562; Thr-dehyd; 1.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR044561; ACT_ThrD-II-like.
DR InterPro; IPR005789; Thr_deHydtase_catblc.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR01127; ilvA_1Cterm; 1.
DR PANTHER; PTHR48078:SF6; ACT DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48078; THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF00291; PALP; 1.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR PROSITE; PS51671; ACT; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00023304};
KW Branched-chain amino acid biosynthesis {ECO:0000256|ARBA:ARBA00023304};
KW Isoleucine biosynthesis {ECO:0000256|ARBA:ARBA00022624};
KW Lyase {ECO:0000313|EMBL:ACJ00531.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000001591}.
FT DOMAIN 349..425
FT /note="ACT"
FT /evidence="ECO:0000259|PROSITE:PS51671"
SQ SEQUENCE 427 AA; 44736 MW; 846D17528F9E6405 CRC64;
MSQRPPSSPD AAAPDAAAPD TAALPVSLDD IRAAAEALRG QVVETPCIPS RTLSQITGAE
IWVKFENLQF TASFKERGAF NKLRTLTEEE RRRGVVAMSA GNHAQGVAYH AGRLGVPATI
VMPEGTPFVK VEHTENFGAR VVLKGANLGE SQIEAERLVR EEGLVLVHPY DDAEVIAGQG
TVALEMLAAA PDLEVLVVPV GGGGLISGIA TAAKAVKPDI EVVGVEVEAY AAVAQALRGE
PPHVGGDTIA EGIAVKNVGR LTLQIIRALV DEVMLVPDAE VERAVALFLN IEKTVAEGAG
AAGLAAVLNH PERFQGRKVG LVLCGGNIDS RLLAQVIMRQ LVREGRLIAL RIAIPDRPGG
LGRITSVVGE AGGNIIEAMH QRLFTTATVK STDIDLTIEC RSARHAAKVV QALRDAGFGV
KILTGGV
//
