ID B6JNK1_HELP2 Unreviewed; 378 AA.
AC B6JNK1;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=VirB8 type IV secretion protein {ECO:0000313|EMBL:ACJ08479.1};
GN Name=virB8-2 {ECO:0000313|EMBL:ACJ08479.1};
GN OrderedLocusNames=HPP12_1328 {ECO:0000313|EMBL:ACJ08479.1};
OS Helicobacter pylori (strain P12).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=570508 {ECO:0000313|EMBL:ACJ08479.1, ECO:0000313|Proteomes:UP000008198};
RN [1] {ECO:0000313|Proteomes:UP000008198}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P12 {ECO:0000313|Proteomes:UP000008198};
RA Fischer W., Windhager L., Karnholz A., Zeiller M., Zimmer R., Haas R.;
RT "The complete genome sequence of Helicobacter pylori strain P12.";
RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACJ08479.1, ECO:0000313|Proteomes:UP000008198}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P12 {ECO:0000313|EMBL:ACJ08479.1,
RC ECO:0000313|Proteomes:UP000008198};
RX PubMed=20478826; DOI=10.1093/nar/gkq378;
RA Fischer W., Windhager L., Rohrer S., Zeiller M., Karnholz A., Hoffmann R.,
RA Zimmer R., Haas R.;
RT "Strain-specific genes of Helicobacter pylori: genome evolution driven by a
RT novel type IV secretion system and genomic island transfer.";
RL Nucleic Acids Res. 38:6089-6101(2010).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001217; ACJ08479.1; -; Genomic_DNA.
DR RefSeq; WP_000067683.1; NC_011498.1.
DR AlphaFoldDB; B6JNK1; -.
DR KEGG; hpp:HPP12_1328; -.
DR HOGENOM; CLU_735234_0_0_7; -.
DR Proteomes; UP000008198; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd16424; VirB8; 1.
DR Gene3D; 3.10.450.230; VirB8 protein; 1.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR007430; VirB8.
DR Pfam; PF04335; VirB8; 1.
DR SUPFAM; SSF54427; NTF2-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 147..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 137..333
FT /note="Bacterial virulence protein VirB8"
FT /evidence="ECO:0000259|Pfam:PF04335"
FT REGION 345..378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..378
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 378 AA; 44003 MW; 436A709D1C4414A3 CRC64;
MSNLQELREH LKELENSFEI GSFTKENIKE YAKCFFMSLS MFLEEQEKNQ QEEFLEQDTK
ENQEELIKSI QTSIAKNQEL EKISFEKWEN KIQERVLPKL KRIVTHKLQE SITSSINTQL
ESFKKDELDL SSVFEIQRKN TQIAYRLAIG GLIGIIALSI AIFIMMPLKE NTPYFIDFAN
SDKHFAVVQR ADTKVDYGEA FLRNLVGSYI TARETINHID DKIRLNETIR EQSSEEVWKT
LEQLVSGKGS IYSNSNMDRE IKIINISIYK QGKQQNIAVA DIVAKVFDKG YLISEKRYRV
SLIYHFKPLI QFDYSSMPKN PTGFIVDKYS LSEIASIKAL DKTYKKVERP HSKIEYKKQN
PTNPQNNPAN IPNNKEEQ
//
