ID B6K185_SCHJY Unreviewed; 944 AA.
AC B6K185;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Inner centromere protein ARK-binding domain-containing protein {ECO:0000259|Pfam:PF03941};
GN Name=pic1 {ECO:0000313|JaponicusDB:SJAG_02807};
GN ORFNames=SJAG_02807 {ECO:0000313|EMBL:EEB07706.1};
OS Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=402676 {ECO:0000313|EMBL:EEB07706.1, ECO:0000313|Proteomes:UP000001744};
RN [1] {ECO:0000313|EMBL:EEB07706.1, ECO:0000313|Proteomes:UP000001744}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=yFS275 / FY16936 {ECO:0000313|Proteomes:UP000001744};
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle
CC {ECO:0000256|ARBA:ARBA00004186}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the INCENP family.
CC {ECO:0000256|ARBA:ARBA00010042}.
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DR EMBL; KE651166; EEB07706.1; -; Genomic_DNA.
DR RefSeq; XP_002173999.1; XM_002173963.2.
DR AlphaFoldDB; B6K185; -.
DR STRING; 402676.B6K185; -.
DR EnsemblFungi; EEB07706; EEB07706; SJAG_02807.
DR GeneID; 7049470; -.
DR JaponicusDB; SJAG_02807; pic1.
DR VEuPathDB; FungiDB:SJAG_02807; -.
DR eggNOG; KOG1181; Eukaryota.
DR HOGENOM; CLU_296495_0_0_1; -.
DR OMA; TMDWLNE; -.
DR OrthoDB; 1368690at2759; -.
DR Proteomes; UP000001744; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR Gene3D; 6.10.250.2990; -; 1.
DR InterPro; IPR005635; Inner_centromere_prot_ARK-bd.
DR PANTHER; PTHR13142; INNER CENTROMERE PROTEIN; 1.
DR PANTHER; PTHR13142:SF1; INNER CENTROMERE PROTEIN; 1.
DR Pfam; PF03941; INCENP_ARK-bind; 1.
PE 3: Inferred from homology;
KW Chromosome partition {ECO:0000256|ARBA:ARBA00022829};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001744}.
FT DOMAIN 846..904
FT /note="Inner centromere protein ARK-binding"
FT /evidence="ECO:0000259|Pfam:PF03941"
FT REGION 91..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 132..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 250..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 392..502
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 516..669
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 702..738
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 786..928
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 134..158
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..185
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..219
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 250..282
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..410
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 450..482
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 516..538
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..600
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 623..643
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 644..664
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 718..732
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 796..817
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 875..916
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 944 AA; 104745 MW; 61BE43DB4E1ABF0A CRC64;
MNSVGSEPWV TKEIGYSEKI RKEKGKEFAF LVSETMDWLN EHMSEISKLQ FETDFYSLVK
TPSRFKAKYG TPALSPVRRC MLPTPKQLLA SFQQQDESVE SEEHMLVPSD PAALKNHQVH
DSSDSLLDII DNGAAQHAKE HEKEEEEEEV KRESALSEDS VTLVKQLTKQ ESTSAEKDDA
KDNSTTSKGN ELQLFKEKSH DSADEVKVKK EKAPKSPVSR HLFSDKILGA KRGIVKPLIE
KFNKIRLPAK RKSEVLLEDE DESKSLKENK RTVTHKPQDI EADPETIAAV ADLTSANVKD
ELSSSSARTS HVTRPFMKRM LSSPTKQDRT SPVRRQTTTI TTPRSERTRV LGALTNRKTS
HAPLTPKISA PVDAVLNAVR NSAAKDFQLA KQKMGSLTPS QVSRSPERHT TVINELPKIP
VMPTYSKLST QQTHQRLKIR GKKNSNPFAD EDTNESSSSS PAKSSSGKTQ EKNTTALTER
LENAAKSKSA DESAARPSST VSEAGLLSRY DLRKPVSRMT SNSSKPVAIR IATASQRELG
NNEKRKAKPT SSLQNNQQHQ PVESMSTSIA AETNDASTHQ NESTVRRTLP SRQMKTLSST
KAAKLRDGKD HSTASSSASF KHESKARSGK DHTGKHPEDA KSDAPSRITT SVSNTTSSWQ
SKLSKRAEEA LRKRKMMTDD IGKSKLVLKP NLTRVASKYS GAPTRELPED KSIGLHNGTL
KKTGSDNSLA SRALPAGGSV GAPKLQKIYE NQEAKHTTNA QLSNYHSKVN MHLGSSSLLA
QSVLRNAKKR SSHDNNGSNN HLLKTPEANI RSFGSKHTGS SGKHHRSPAE STSPLIPSEA
IELPEIDSDY SDSSDDDEQK RKQKLNLPSW AESPELREQL RRQQKLDPDK IFGTIKPPEI
EELFNSKDRP RSRFRPRSSS ADWSSQDRLT QAEIEQYKKQ MGYL
//
