ID B6K5U8_SCHJY Unreviewed; 1104 AA.
AC B6K5U8;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 2.
DT 24-JAN-2024, entry version 63.
DE SubName: Full=Tubulin specific chaperone cofactor D {ECO:0000313|EMBL:EEB08902.2};
GN Name=alp1 {ECO:0000313|JaponicusDB:SJAG_04074};
GN ORFNames=SJAG_04074 {ECO:0000313|EMBL:EEB08902.2};
OS Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=402676 {ECO:0000313|EMBL:EEB08902.2, ECO:0000313|Proteomes:UP000001744};
RN [1] {ECO:0000313|EMBL:EEB08902.2, ECO:0000313|Proteomes:UP000001744}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=yFS275 / FY16936 {ECO:0000313|Proteomes:UP000001744};
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
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DR EMBL; KE651167; EEB08902.2; -; Genomic_DNA.
DR RefSeq; XP_002175195.2; XM_002175159.2.
DR AlphaFoldDB; B6K5U8; -.
DR STRING; 402676.B6K5U8; -.
DR EnsemblFungi; EEB08902; EEB08902; SJAG_04074.
DR GeneID; 7047598; -.
DR JaponicusDB; SJAG_04074; alp1.
DR VEuPathDB; FungiDB:SJAG_04074; -.
DR eggNOG; KOG1943; Eukaryota.
DR HOGENOM; CLU_280203_0_0_1; -.
DR OMA; RDASCYF; -.
DR OrthoDB; 5477080at2759; -.
DR Proteomes; UP000001744; Unassembled WGS sequence.
DR GO; GO:0048487; F:beta-tubulin binding; IBA:GO_Central.
DR GO; GO:0005096; F:GTPase activator activity; IBA:GO_Central.
DR GO; GO:0000226; P:microtubule cytoskeleton organization; IBA:GO_Central.
DR GO; GO:0007023; P:post-chaperonin tubulin folding pathway; IEA:InterPro.
DR GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR GO; GO:0007021; P:tubulin complex assembly; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR033162; TBCD.
DR InterPro; IPR022577; Tubulin_specific_chaperoneD_C.
DR PANTHER; PTHR12658; BETA-TUBULIN COFACTOR D; 1.
DR PANTHER; PTHR12658:SF0; TUBULIN-SPECIFIC CHAPERONE D; 1.
DR Pfam; PF12612; TFCD_C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001744}.
FT DOMAIN 830..1003
FT /note="Tubulin-specific chaperone D C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12612"
SQ SEQUENCE 1104 AA; 126862 MW; AE1BB6F0CDB2BD1D CRC64;
MSVTKYEEQQ DYPDLYINEH ELTEATRDGF RNLFLSNDPS KKLLLSEKLI QNLQEFQAQP
LLLDKVIGEF LPELNSRFLH PTERLISCSL FYELCKIKGY KTLLLSFVTD ISLIERLVDE
LSNDECESWK VHYTYLLWLS QVIQAPFPLK TLEQKPNLEV RVLNLLISFL KLPGKNRDAS
VVALGRFLSR SDTVQLLPQF IHYAISLLNG SKQTDYSILG CLETVAQFLK FVERSVFLPF
EDLIFRFLRL YKKFITPEDT LLQKFACKAA YRFALLLLPL KSSEQWRFSK YALSNFEQYP
EDNNVEVHED VEYSVDILLD SITHKDTVVR WSAAKGLARI VERLPWFFAE QVMDAVFDIL
MENAFRDPVT NEWNLTVTNP NSWHGAVLCF SELASHGLLK KRTLDKLVPL MLLSLVYEVR
NGTKVSGSNV RDAADYFVWS LYRVYTEKEL ASYTEELAIQ VALTALFDRE LNVRRASSAA
FQEMTGRNTC VPYGVHLVST LGFYAVTDRT ACFTKISVEV AQYDSYCLPI INRLIDKLHY
WDAEIRSLAV QALAALACVY PHEILPKVQT LIERLSTSQL GHIHGDLLAL CAIYQAVEST
NKTLLEKSYT QFLYNYEQYL PVTLFHEFQG FELSSILLSF ISCVCKNAAP PDNDFLERSL
SHLSAAISLQ DEMLHSKIAE TFALLYQYEH IAVKTSVFLK TLNTSSLLST QLCYVLMFAA
VKWKESQYYV PVFQALSTLY TDKKTCIELQ KEVSLFCYNS VDYVLQNLEE NYLDTFVSLV
FNFGNNYHID SRGDTGSWVR QYAVQAIAVL LLGDAEVKRL KESQIRTSLS LLVRLRFDRI
DKIRVSANDA LVNSRNHYLI KGDKPLCDVL ESFSSTTWAA SNYVSKTTIN LLNVPSMFDS
AFHGLVLLLC DGFGNEVVTS AYSNFLLYLD LLPVSKSSSE FTALEDIFDF LEHFISNAAT
EVPLWVSSVR LLTSLLVRGY FLNFISPKRL LLISFHAQRR VKQFKSFSTL QYILRLYQST
LLVQHEKVWV QVMKYITNLL VHPMLKLRLH VAECLLYGLQ QPHAIPLPSS IYEQLLTTDW
LSNTPAHIKL IQSLKDQWQR KVKT
//
