ID   B6QL54_TALMQ            Unreviewed;       872 AA.
AC   B6QL54;
DT   16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   SubName: Full=SAM and PH domain protein (Boi1), putative {ECO:0000313|EMBL:EEA21831.1};
GN   ORFNames=PMAA_056230 {ECO:0000313|EMBL:EEA21831.1};
OS   Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333)
OS   (Penicillium marneffei).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC   Talaromyces sect. Talaromyces.
OX   NCBI_TaxID=441960 {ECO:0000313|EMBL:EEA21831.1, ECO:0000313|Proteomes:UP000001294};
RN   [1] {ECO:0000313|Proteomes:UP000001294}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 18224 / CBS 334.59 / QM 7333
RC   {ECO:0000313|Proteomes:UP000001294};
RX   PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA   Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT   "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT   (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT   (ATCC10500).";
RL   Genome Announc. 3:E0155914-E0155914(2015).
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DR   EMBL; DS995903; EEA21831.1; -; Genomic_DNA.
DR   RefSeq; XP_002150440.1; XM_002150404.1.
DR   AlphaFoldDB; B6QL54; -.
DR   VEuPathDB; FungiDB:PMAA_056230; -.
DR   HOGENOM; CLU_009306_0_0_1; -.
DR   OrthoDB; 1405875at2759; -.
DR   PhylomeDB; B6QL54; -.
DR   Proteomes; UP000001294; Unassembled WGS sequence.
DR   CDD; cd09535; SAM_BOI-like_fungal; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR001660; SAM.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   PANTHER; PTHR12844; CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS; 1.
DR   PANTHER; PTHR12844:SF42; CONNECTOR ENHANCER OF KSR PROTEIN CNK; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF07647; SAM_2; 1.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00454; SAM; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50105; SAM_DOMAIN; 1.
PE   4: Predicted;
KW   Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001294};
KW   Transferase {ECO:0000256|ARBA:ARBA00022676}.
FT   DOMAIN          183..247
FT                   /note="SAM"
FT                   /evidence="ECO:0000259|PROSITE:PS50105"
FT   DOMAIN          714..854
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          51..84
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          250..306
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        60..80
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        250..277
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        281..299
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   872 AA;  97434 MW;  8A24EE306E759740 CRC64;
     MATIDNTGYV TLEMLQALSK QSIFRRTTIG RPRSIASDAT EIFDTDFESD CDRSYNDDSS
     RRSAGSLVAD SVTTADTPRD VPTPDSGALS AFDFHFDEKP IMGPNGPHLF RSSMSSDEMS
     YEVDFMLAKT PTVAIFRRSV TEERRDTPLP GHDDSTEYTP QAQELKSINA AVSALDESEV
     RSWSPPDVVR WMQESGFDDS VIEKFFINDI SGAILLDLRS EDLKELDIQS FGKRRHVMNS
     IQHLRDSFML PNNETSTSSH DHSSTDCTSS SESASTPTKD SNKKKHRRRR NHRSHKKSLV
     AHKDLNPDDS ASIVAIEQFL PKPHRCSKGE NCRKWQKQQR KIARLAKDLP IDVDAARLMS
     EDYEDQPPLT SKSLPNMDPM PTPSIVASSD VLGPEQTPVF QISEEKLSEI GPRDPQENVR
     QYLNFQHLSK LQPVPQVASK PDLCSSPDID SPDSIRTTTS LADNLRSLPK LTIPVNHHIV
     VPGTFSASLS AQRTVTPSIL RRQPNFATNS IDGTLHSALP QPMTYGSCIS PADYVGSPSD
     FYRSHDFYQQ TSPLSEIDVP VTAIMSAGPV QRHESQSVPP NMRFGHHLRV IPDPFVRPRS
     TKPEIHRAGP TIQILDSVDE ARPSHDTVDV PVTAIPLGPI ERTESQSVPP NMRFGRDFYV
     TVDPINRPAS TKANNYRYPS MINSALDRVD ELGPIDTEED FATTPRANPR SANDITHSGW
     MRKRKTTRML RHEWEDHHFT LKGTRLAMYE DERASRRDSK AIEYIDVDDY AVACSSIPSS
     SKLTAAFKKT VLKRKSSAQD EAAFAFSLIP APSGKTTGVE RRNVFVSNGK SHHFAVKTRD
     ERIDWMRELM LAKALKKGKD SGDAVHVNGQ AF
//