ID   B7HQ08_BACC7            Unreviewed;       503 AA.
AC   B7HQ08;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 72.
DE   SubName: Full=Neutral metalloprotease {ECO:0000313|EMBL:ACJ78111.1};
GN   OrderedLocusNames=BCAH187_A2324 {ECO:0000313|EMBL:ACJ78111.1};
OS   Bacillus cereus (strain AH187).
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=405534 {ECO:0000313|EMBL:ACJ78111.1, ECO:0000313|Proteomes:UP000002214};
RN   [1] {ECO:0000313|EMBL:ACJ78111.1, ECO:0000313|Proteomes:UP000002214}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AH187 {ECO:0000313|EMBL:ACJ78111.1,
RC   ECO:0000313|Proteomes:UP000002214};
RA   Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Kolsto A.B.,
RA   Okstad O.A., Ravel J., Sutton G.;
RT   "Genome sequence of Bacillus cereus AH187.";
RL   Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP001177; ACJ78111.1; -; Genomic_DNA.
DR   AlphaFoldDB; B7HQ08; -.
DR   KEGG; bcr:BCAH187_A2324; -.
DR   HOGENOM; CLU_040771_0_0_9; -.
DR   Proteomes; UP000002214; Chromosome.
DR   GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.170.10; -; 1.
DR   Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR   InterPro; IPR011096; FTP_domain.
DR   InterPro; IPR025711; PepSY.
DR   InterPro; IPR001842; Peptidase_M36.
DR   InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR   PANTHER; PTHR33794; BACILLOLYSIN; 1.
DR   PANTHER; PTHR33794:SF3; NEUTRAL PROTEASE B; 1.
DR   Pfam; PF07504; FTP; 1.
DR   Pfam; PF03413; PepSY; 1.
DR   Pfam; PF02128; Peptidase_M36; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW   ECO:0000313|EMBL:ACJ78111.1}; Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           26..503
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002856683"
FT   DOMAIN          75..104
FT                   /note="FTP"
FT                   /evidence="ECO:0000259|Pfam:PF07504"
FT   DOMAIN          122..192
FT                   /note="PepSY"
FT                   /evidence="ECO:0000259|Pfam:PF03413"
SQ   SEQUENCE   503 AA;  54576 MW;  2E1ABB2C2F91FF91 CRC64;
     MFNKKMVAMA MTVPLVMGTI STVSALEKQQ QVKLEAYSPQ KKATEYLKEN AAQYGLKADL
     SDLQYISTTE TSVASYVRFQ QVVNGAPVFS KQITVTLNGE GKGVLAVSDY QSVKGVKEAT
     TKISEKDAIQ KSMAYVGEVS EQNLWAPTEK EFGYIVEEGI ARPVYKVVVH SNNPFGAWET
     FVDAENGKLI KKVDINRKAE GSGKVFLPNP VVSSGSKVGL KDNNDADSTA LTNQLKTVTL
     KGLDGTGFLI GEYVTISSKA KTKSTNLQFN YTRANDSFED VMSYYHIDTL QRYIQSLGFK
     NINNRSIKVN VNGTTADNSF YSPTTKALTF GTGGVDDAED AGIIAHEYGH SIQDNQVPGF
     GSSAEGGAMG EGFGDFLGAT YEDAVSTTGY GKACVGEWDA TAYSSSDPTC LRRLDNNKVY
     PKDITNEVHD DGEIWAQGQY EMAQAFGRDV ATKIILQSHW SLTPNSKFSD GAKAIKQADA
     LLYGGQHAAD IDRIWAARGI STN
//