ID   B7ICL3_THEAB            Unreviewed;       883 AA.
AC   B7ICL3;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 91.
DE   SubName: Full=Endo-beta-N-acetylglucosaminidase {ECO:0000313|EMBL:ACJ75740.1};
GN   OrderedLocusNames=THA_1295 {ECO:0000313|EMBL:ACJ75740.1};
OS   Thermosipho africanus (strain TCF52B).
OC   Bacteria; Thermotogota; Thermotogae; Thermotogales; Fervidobacteriaceae;
OC   Thermosipho.
OX   NCBI_TaxID=484019 {ECO:0000313|EMBL:ACJ75740.1, ECO:0000313|Proteomes:UP000002453};
RN   [1] {ECO:0000313|EMBL:ACJ75740.1, ECO:0000313|Proteomes:UP000002453}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TCF52B {ECO:0000313|EMBL:ACJ75740.1,
RC   ECO:0000313|Proteomes:UP000002453};
RX   PubMed=19124572; DOI=10.1128/JB.01448-08;
RA   Nesboe C.L., Bapteste E., Curtis B., Dahle H., Lopez P., Macleod D.,
RA   Dlutek M., Bowman S., Zhaxybayeva O., Birkeland N.-K., Doolittle W.F.;
RT   "The genome of Thermosipho africanus TCF52B: lateral genetic connections to
RT   the Firmicutes and Archaea.";
RL   J. Bacteriol. 191:1974-1978(2009).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}.
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DR   EMBL; CP001185; ACJ75740.1; -; Genomic_DNA.
DR   RefSeq; WP_012580126.1; NC_011653.1.
DR   AlphaFoldDB; B7ICL3; -.
DR   STRING; 484019.THA_1295; -.
DR   CAZy; CBM32; Carbohydrate-Binding Module Family 32.
DR   CAZy; GH85; Glycoside Hydrolase Family 85.
DR   KEGG; taf:THA_1295; -.
DR   eggNOG; COG3291; Bacteria.
DR   eggNOG; COG4724; Bacteria.
DR   HOGENOM; CLU_008357_0_0_0; -.
DR   OrthoDB; 1089471at2; -.
DR   Proteomes; UP000002453; Chromosome.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0033925; F:mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR   CDD; cd06547; GH85_ENGase; 1.
DR   CDD; cd00146; PKD; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR   InterPro; IPR032979; ENGase.
DR   InterPro; IPR000421; FA58C.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR005201; Glyco_hydro_85.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR022409; PKD/Chitinase_dom.
DR   InterPro; IPR035986; PKD_dom_sf.
DR   PANTHER; PTHR13246:SF1; CYTOSOLIC ENDO-BETA-N-ACETYLGLUCOSAMINIDASE; 1.
DR   PANTHER; PTHR13246; ENDO BETA N-ACETYLGLUCOSAMINIDASE; 1.
DR   Pfam; PF00754; F5_F8_type_C; 1.
DR   Pfam; PF03644; Glyco_hydro_85; 1.
DR   SMART; SM00089; PKD; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   SUPFAM; SSF49299; PKD domain; 1.
DR   PROSITE; PS50022; FA58C_3; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT   DOMAIN          735..880
FT                   /note="F5/8 type C"
FT                   /evidence="ECO:0000259|PROSITE:PS50022"
SQ   SEQUENCE   883 AA;  101216 MW;  8F88B60B437F5F0E CRC64;
     MKKIIIILFS ILSIAIFAQI PESSYWYPND ILDWSPQTDS QAIYNVSHVP LARRVIGSPI
     TDSASKDIKI MTLSIMNPST SGMPSQGSNN SFKAYPFTFW QYVDYLVAWA GSAGEGIIVP
     PSADVIDAAH KNGVYVLGTI FFPPNVYGGR RNWVDQLLRK ENGKFVIADK LIEITKYYGF
     DGWFINQETN GCKDSHVKDM IDFLNYIKEK APWMKLVWYD SMSNTGAIEW QGELNEKNVV
     FLKNNDKYIS DAIFIDFRWQ SLKRPETIEN TINTMKKYNI SKDRVFVGFD LQANGYYTYS
     NWPKIIDENG KLKVSLGFYC PSWAYYSSKE IKEFWDKEET LWIADHPVLN YHSKEDFFKI
     EWNKDYEQYK WQSPAKFVVE KSPVTSLPFI TFFNAGHGYK FFIDGKVAKD SEWNNRSMMD
     VFPTYRWKID GNDVNISVDY SDAYYGGSSL KFEGKLKKDQ ETNVTLYITD LKINDNTTLE
     SVIKGTGNIK VSLVLNYSDN TSKEFPLKFF NDWVNTIYNL ENNKTITSIS LKIVAIEDTS
     YSFNLGMIGL IPVKNYDTHV GDVKIDNIEF KEGLYAQINL HCENSKAKYY EIYRILQNGE
     RRLVWVSYNP YTYITQIKRD GKEKFTTLEV VGVSEGFTKS TPKKVTFQWP PYPKPKANFE
     VSNTIIFPES TVTFKNLSSE VTEKVLWILP GATPNVSREW NPTVTYKEEG IYPAILVAIN
     SEGEDVKIFN PLIVVTKKAK EIKNLALNKK TYASSNVPAE KPSMAVDGTV ENNSKWCAVG
     DLPHWIVIDF EKEVIISSVT IKHAEAGHES ADWNTKDFRL QVSNDGINWK DVAIVRNNTK
     GVSTHSFAPV KARFFRLFIE TPTQVGDKAA RIYEIEVYGL ESF
//