ID   B7JFK8_BACC0            Unreviewed;       544 AA.
AC   B7JFK8;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 80.
DE   SubName: Full=Putative macrolide efflux pump {ECO:0000313|EMBL:ACK90994.1};
GN   OrderedLocusNames=BCAH820_5266 {ECO:0000313|EMBL:ACK90994.1};
OS   Bacillus cereus (strain AH820).
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=405535 {ECO:0000313|EMBL:ACK90994.1, ECO:0000313|Proteomes:UP000001363};
RN   [1] {ECO:0000313|EMBL:ACK90994.1, ECO:0000313|Proteomes:UP000001363}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AH820 {ECO:0000313|EMBL:ACK90994.1,
RC   ECO:0000313|Proteomes:UP000001363};
RA   Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Hoffmaster A.,
RA   Ravel J., Sutton G.;
RT   "Genome sequence of Bacillus cereus AH820.";
RL   Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP001283; ACK90994.1; -; Genomic_DNA.
DR   RefSeq; WP_000153740.1; NC_011773.1.
DR   AlphaFoldDB; B7JFK8; -.
DR   KEGG; bcu:BCAH820_5266; -.
DR   HOGENOM; CLU_000604_36_0_9; -.
DR   Proteomes; UP000001363; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   CDD; cd03221; ABCF_EF-3; 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR032781; ABC_tran_Xtn.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR42855:SF2; ABC TRANSPORTER ATP-BINDING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR42855; ABC TRANSPORTER ATP-BINDING SUBUNIT; 1.
DR   Pfam; PF00005; ABC_tran; 2.
DR   Pfam; PF12848; ABC_tran_Xtn; 1.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          4..193
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000259|PROSITE:PS50893"
FT   DOMAIN          288..496
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000259|PROSITE:PS50893"
FT   COILED          171..216
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   544 AA;  61553 MW;  1EF6B854D54C871F CRC64;
     MTILFARNIE KGFGNRTLFT LPSLEIQSHD RIGIVGVNGA GKSTLLQILS KEIEADKGIV
     THHSSISIIP QISEELPKVA SSTAKGKWNI SNISNSMSGG ERMLLKIAHA LEQDAGILFA
     DEPTSHLDMF GTEQLEKALL SYKGALVLIS HDREFLDNIC TKIIEIEDGI IQEYKGNYSN
     YRKQKERERT QKQAEYEQYI NEKERLEKSI LQKKQRASSM TKIPTRFSSS ESKLYKLSGA
     HGQEQVSKAA KALETRLEKL EKKEKPKELS QAQFDVQYHT PIHSKVAVQF NKATKKIGDR
     TLFKNMNGTI APGAKLAILG ANGSGKTTLF NMLLANERGI QLSKRCKIGY FEQTLSILKT
     DKTILENVLE ETNYTESFVR TILARLLFRR EDVHKPVHVL SGGERMKVAL AKVFLGNYNM
     LLLDEPTNYL DLATQEELES MLQEYPGTIL FISHDRAFIR SVADHILQVD ESEPRVFHGN
     YEQYTNRTTD ASVNVTAQEL LRLQTKLTEI IGRISIPNHH DDITSLEQEY ETLLVKIRKC
     KEAL
//