ID B7KN36_METC4 Unreviewed; 294 AA.
AC B7KN36;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=5-carboxymethyl-2-hydroxymuconate Delta-isomerase {ECO:0000313|EMBL:ACK85153.1};
DE EC=5.3.3.10 {ECO:0000313|EMBL:ACK85153.1};
GN OrderedLocusNames=Mchl_4377 {ECO:0000313|EMBL:ACK85153.1};
OS Methylorubrum extorquens (strain CM4 / NCIMB 13688) (Methylobacterium
OS extorquens).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylobacteriaceae; Methylorubrum.
OX NCBI_TaxID=440085 {ECO:0000313|EMBL:ACK85153.1, ECO:0000313|Proteomes:UP000002385};
RN [1] {ECO:0000313|Proteomes:UP000002385}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CM4 / NCIMB 13688 {ECO:0000313|Proteomes:UP000002385};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA Marx C., Richardson P.;
RT "Complete sequence of chromosome of Methylobacterium chloromethanicum
RT CM4.";
RL Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACK85153.1, ECO:0000313|Proteomes:UP000002385}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CM4 / NCIMB 13688 {ECO:0000313|Proteomes:UP000002385};
RX PubMed=22887658; DOI=10.1128/JB.01009-12;
RA Marx C.J., Bringel F., Chistoserdova L., Moulin L., Farhan Ul Haque M.,
RA Fleischman D.E., Gruffaz C., Jourand P., Knief C., Lee M.C., Muller E.E.,
RA Nadalig T., Peyraud R., Roselli S., Russ L., Goodwin L.A., Ivanova N.,
RA Kyrpides N., Lajus A., Land M.L., Medigue C., Mikhailova N., Nolan M.,
RA Woyke T., Stolyar S., Vorholt J.A., Vuilleumier S.;
RT "Complete genome sequences of six strains of the genus Methylobacterium.";
RL J. Bacteriol. 194:4746-4748(2012).
CC -!- SIMILARITY: Belongs to the FAH family. {ECO:0000256|ARBA:ARBA00010211}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001298; ACK85153.1; -; Genomic_DNA.
DR RefSeq; WP_015952238.1; NC_011757.1.
DR AlphaFoldDB; B7KN36; -.
DR KEGG; mch:Mchl_4377; -.
DR HOGENOM; CLU_028458_3_4_5; -.
DR Proteomes; UP000002385; Chromosome.
DR GO; GO:0008704; F:5-carboxymethyl-2-hydroxymuconate delta-isomerase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.90.850.10; Fumarylacetoacetase-like, C-terminal domain; 1.
DR InterPro; IPR011234; Fumarylacetoacetase-like_C.
DR InterPro; IPR036663; Fumarylacetoacetase_C_sf.
DR PANTHER; PTHR42796:SF4; FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A; 1.
DR PANTHER; PTHR42796; FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A-RELATED; 1.
DR Pfam; PF01557; FAA_hydrolase; 1.
DR SUPFAM; SSF56529; FAH; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000313|EMBL:ACK85153.1}.
FT DOMAIN 73..278
FT /note="Fumarylacetoacetase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01557"
SQ SEQUENCE 294 AA; 31404 MW; F84E725C3CFBEB98 CRC64;
MKLIRHGASG DEKPGLVDAK GGLRDLSGTL RDLAGPGLSR ESLDRLARID PESLPLLPPG
TRLGPCVGGT RNFVAIGLNY ADHAAETGAA IPAEPIIFNK APSCIVGPND TVILPKASAK
TDWEVELAVV IGARASYVHA NEALRYVAGV CICNDLSERE FQMERGGTWT KGKGCPTFGP
LGPWLVTLDE IPDLKNLSMS LDLNGRRMQS GSTATMIFDV AQIVAYVSHF MMLEPGDVIT
TGTPPGVGLG MKPPRYLRSD DEMVLRIDGL GEQRQRVVAF DDWTAKVAAG EPTN
//
