ID B7KQW3_METC4 Unreviewed; 575 AA.
AC B7KQW3;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:ACK85504.1};
GN OrderedLocusNames=Mchl_4730 {ECO:0000313|EMBL:ACK85504.1};
OS Methylorubrum extorquens (strain CM4 / NCIMB 13688) (Methylobacterium
OS extorquens).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylobacteriaceae; Methylorubrum.
OX NCBI_TaxID=440085 {ECO:0000313|EMBL:ACK85504.1, ECO:0000313|Proteomes:UP000002385};
RN [1] {ECO:0000313|Proteomes:UP000002385}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CM4 / NCIMB 13688 {ECO:0000313|Proteomes:UP000002385};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA Marx C., Richardson P.;
RT "Complete sequence of chromosome of Methylobacterium chloromethanicum
RT CM4.";
RL Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACK85504.1, ECO:0000313|Proteomes:UP000002385}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CM4 / NCIMB 13688 {ECO:0000313|Proteomes:UP000002385};
RX PubMed=22887658; DOI=10.1128/JB.01009-12;
RA Marx C.J., Bringel F., Chistoserdova L., Moulin L., Farhan Ul Haque M.,
RA Fleischman D.E., Gruffaz C., Jourand P., Knief C., Lee M.C., Muller E.E.,
RA Nadalig T., Peyraud R., Roselli S., Russ L., Goodwin L.A., Ivanova N.,
RA Kyrpides N., Lajus A., Land M.L., Medigue C., Mikhailova N., Nolan M.,
RA Woyke T., Stolyar S., Vorholt J.A., Vuilleumier S.;
RT "Complete genome sequences of six strains of the genus Methylobacterium.";
RL J. Bacteriol. 194:4746-4748(2012).
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DR EMBL; CP001298; ACK85504.1; -; Genomic_DNA.
DR RefSeq; WP_015952493.1; NC_011757.1.
DR AlphaFoldDB; B7KQW3; -.
DR KEGG; mch:Mchl_4730; -.
DR HOGENOM; CLU_033985_0_0_5; -.
DR Proteomes; UP000002385; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR PANTHER; PTHR30097; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR PANTHER; PTHR30097:SF4; SLR6042 PROTEIN; 1.
DR Pfam; PF13437; HlyD_3; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..34
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 35..575
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002858771"
FT TRANSMEM 183..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 33..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 229..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 575 AA; 59749 MW; 9BFE1E5D4B446BEF CRC64;
MTFLKNDAHG RPRGRAAGLA MLILASCFAA PARAGGGDDH SHGPAPASSA AAAQGTPRIS
IQSDLYQVVG TLKGDRLTLY VDRSEDNEPV TGATVSVTVE GEAMPAAPNA DGTYAVSSPH
LAEPGSNDLV IQVAGPDGED LLIAALVVAE PARPVAEAGT GHVHPGMPFL AHLREWLSQP
EPGGAWALAV FAVGLALGLA LRSRRMRPAA FVAGAVLVVA LTGTAFAHGG EDHDHDAPTA
APGSNTPQRL PDGSVFVPKS SQRILEVRTT TARPTEVEGA TRLIGKVIPD PNRGGLVQSI
GGGRVIAPEA GMPRLGQAVR KGEVLARVER PIIQADQAIV VEKVGEIEQQ IGLAEAKLAR
ARKLVASGAG TAISVSDLEI ELEGMRRRRA AVSDIQTTPE TLTAPADGVI ASTRVVAGQV
VQPQDVLFQV IHPGSLWVEA LSFEDAPTGT GTTALTVDGA TLRLEPKGVS RALQQQATVL
QFAVVDPPDN LRVGQPVTVL AATGTSANGI VLPRNAVVRG TGGEAMVWRH AAPERFEPRQ
VRVEPVDATR VVVRAGVKEG ERVVVRGADL INQIR
//
