ID   B7LM60_ESCF3            Unreviewed;       543 AA.
AC   B7LM60;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN   OrderedLocusNames=EFER_0898 {ECO:0000313|EMBL:CAQ88433.1};
OS   Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM
OS   14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585054 {ECO:0000313|EMBL:CAQ88433.1, ECO:0000313|Proteomes:UP000000745};
RN   [1] {ECO:0000313|Proteomes:UP000000745}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35469 / DSM 13698 / BCRC 15582 / CCUG 18766 / IAM 14443 /
RC   JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73
RC   {ECO:0000313|Proteomes:UP000000745};
RX   PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA   Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA   Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H.,
RA   Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.,
RA   Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C.,
RA   Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S.,
RA   Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J.,
RA   Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT   "Organised genome dynamics in the Escherichia coli species results in
RT   highly diverse adaptive paths.";
RL   PLoS Genet. 5:E1000344-E1000344(2009).
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DR   EMBL; CU928158; CAQ88433.1; -; Genomic_DNA.
DR   AlphaFoldDB; B7LM60; -.
DR   KEGG; efe:EFER_0898; -.
DR   HOGENOM; CLU_019123_3_0_6; -.
DR   Proteomes; UP000000745; Chromosome.
DR   CDD; cd01465; vWA_subgroup; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR022156; Uncharacterised_YfbK_N.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   InterPro; IPR021908; YfbK_C.
DR   PANTHER; PTHR10579; CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR; 1.
DR   PANTHER; PTHR10579:SF43; LOW QUALITY PROTEIN: EPITHELIAL CHLORIDE CHANNEL PROTEIN-LIKE ISOFORM X1-RELATED; 1.
DR   Pfam; PF00092; VWA; 1.
DR   Pfam; PF12450; vWF_A; 1.
DR   Pfam; PF12034; YfbK_C; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
FT   DOMAIN          183..360
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
SQ   SEQUENCE   543 AA;  59548 MW;  1A5B5DAF67EF6602 CRC64;
     MLPLWFCQIK GIYMRVNKIY IISICGVLLS GCSSSVSSPQ AEERWHYVTM SAYAPSPVQQ
     GQLQQNTARY THHEANPIKQ TAQEPLATFS FDVDTGSYAN VRRFLKTGSL PGADVVRVEE
     LVNYFPLTEA TKKNIPGCKG CEENSPFSIN YELTPAPWNE KHTLLRLDIA ANDIARSKLP
     PTNLVFLIDT SGSMNSDERL PLIKSSLKLL VNELRDQDRI SIVTYAGSAR LLLSSTSGAE
     KNTILNAIAN LQAGGGTNGG AGVAMAYEQA QAGYIKGGVN RILLATDGDF NIGDDPSSVE
     DLVKKQRESG ITLSTLGVGD NNYNEAMMVK IADTGNGNYS YLDSLSEAQK VLSNEMNQTL
     VTVAKDVKAQ IEFNPQQVIE YRQIGYEKRQ LRADEFNNDA VDAGDIGAGK HVTVLFELTL
     AGQQASVDKL RYGKSPASTQ TSNSNELMWV KLRYKAPQGE SSRLVEMPII SSAVTRNFSR
     ASPDMHFLSA VAAYGQKLRG SEYLNKTSWQ QIQSWAQEGK GADQYGYRAE FIQLVGLAES
     LSR
//