ID B7LMX4_ESCF3 Unreviewed; 495 AA.
AC B7LMX4;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Altronate hydrolase {ECO:0000313|EMBL:CAQ91802.1};
DE EC=4.2.1.7 {ECO:0000313|EMBL:CAQ91802.1};
GN Name=uxaA {ECO:0000313|EMBL:CAQ91802.1};
GN OrderedLocusNames=EFER_4384 {ECO:0000313|EMBL:CAQ91802.1};
OS Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM
OS 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=585054 {ECO:0000313|EMBL:CAQ91802.1, ECO:0000313|Proteomes:UP000000745};
RN [1] {ECO:0000313|Proteomes:UP000000745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35469 / DSM 13698 / BCRC 15582 / CCUG 18766 / IAM 14443 /
RC JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73
RC {ECO:0000313|Proteomes:UP000000745};
RX PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H.,
RA Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.,
RA Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C.,
RA Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S.,
RA Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J.,
RA Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT "Organised genome dynamics in the Escherichia coli species results in
RT highly diverse adaptive paths.";
RL PLoS Genet. 5:E1000344-E1000344(2009).
CC -!- SIMILARITY: Belongs to the UxaA family.
CC {ECO:0000256|ARBA:ARBA00010986}.
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DR EMBL; CU928158; CAQ91802.1; -; Genomic_DNA.
DR RefSeq; WP_001199380.1; NC_011740.1.
DR AlphaFoldDB; B7LMX4; -.
DR GeneID; 75059031; -.
DR KEGG; efe:EFER_4384; -.
DR HOGENOM; CLU_029189_0_0_6; -.
DR OrthoDB; 9804574at2; -.
DR Proteomes; UP000000745; Chromosome.
DR GO; GO:0008789; F:altronate dehydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd11613; SAF_AH_GD; 1.
DR Gene3D; 2.30.130.110; -; 1.
DR InterPro; IPR048332; GD_AH_C.
DR InterPro; IPR007392; GD_AH_second.
DR InterPro; IPR013974; SAF.
DR InterPro; IPR044144; UxaA/GarD_SAF.
DR PANTHER; PTHR30536:SF5; ALTRONATE DEHYDRATASE; 1.
DR PANTHER; PTHR30536; ALTRONATE/GALACTARATE DEHYDRATASE; 1.
DR Pfam; PF20629; GD_AH_C; 1.
DR Pfam; PF04295; GD_AH_second; 1.
DR Pfam; PF08666; SAF; 1.
DR SMART; SM00858; SAF; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:CAQ91802.1};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:CAQ91802.1}.
FT DOMAIN 10..81
FT /note="SAF"
FT /evidence="ECO:0000259|SMART:SM00858"
SQ SEQUENCE 495 AA; 54124 MW; 30142C88CA79C3D1 CRC64;
MQYIKIHALD NVAVALADLA EGTEVSVDNQ TVTLRQDVAR GHKFALTDIA KGANVIKYGL
PIGYALADIA AGEHVHAHNT RTNLSDLDQY RYQPDFQDLP AQAADREVQI YRRANGDVGV
RNELWILPTV GCVNGIARQI QNRFLKETNN AEGTDGVFLF SHTYGCSQLG DDHINTRTML
QNMVRHPNAG AVLVIGLGCE NNQVAAFRET LGDIDPERVH FMICQQQDDE IEAGIEHLHQ
LYNVMRNDKR EPGKLSELKF GLECGGSDGL SGITANPMLG RFSDYVIANG GTTVLTEVPE
MFGAEQLLMS HCRDEATFEK LVTMVNDFKQ YFIAHDQPIY ENPSPGNKAG GITTLEDKSL
GCTQKAGSSK VVDVLRYGER LKTPGLNLLS APGNDAVATS ALAGAGCHMV LFSTGRGTPY
GGFVPTVKIA TNSELAAKKK HWIDFDAGQL IHGKAMPQLL EEFIDTIVEF ANGKQTCNER
NDFRELAIFK SGVTL
//
