ID B7MG78_ECO45 Unreviewed; 220 AA.
AC B7MG78;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=Cell division protein DedD {ECO:0000256|HAMAP-Rule:MF_02022};
GN Name=dedD {ECO:0000256|HAMAP-Rule:MF_02022,
GN ECO:0000313|EMBL:CAR03740.1};
GN OrderedLocusNames=ECS88_2461 {ECO:0000313|EMBL:CAR03740.1};
OS Escherichia coli O45:K1 (strain S88 / ExPEC).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=585035 {ECO:0000313|EMBL:CAR03740.1, ECO:0000313|Proteomes:UP000000747};
RN [1] {ECO:0000313|Proteomes:UP000000747}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S88 / ExPEC {ECO:0000313|Proteomes:UP000000747};
RX PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H.,
RA Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.,
RA Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C.,
RA Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S.,
RA Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J.,
RA Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT "Organised genome dynamics in the Escherichia coli species results in
RT highly diverse adaptive paths.";
RL PLoS Genet. 5:E1000344-E1000344(2009).
CC -!- FUNCTION: Non-essential cell division protein that could be required
CC for efficient cell constriction. {ECO:0000256|HAMAP-Rule:MF_02022}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC Rule:MF_02022}; Single-pass membrane protein {ECO:0000256|HAMAP-
CC Rule:MF_02022}. Note=Localizes at the septal ring. {ECO:0000256|HAMAP-
CC Rule:MF_02022}.
CC -!- DOMAIN: The SPOR domain binds septal peptidoglycans and is required to
CC target DedD to the septal ring. {ECO:0000256|HAMAP-Rule:MF_02022}.
CC -!- SIMILARITY: Belongs to the DedD family. {ECO:0000256|HAMAP-
CC Rule:MF_02022}.
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DR EMBL; CU928161; CAR03740.1; -; Genomic_DNA.
DR RefSeq; WP_000157003.1; NC_011742.1.
DR AlphaFoldDB; B7MG78; -.
DR KEGG; ecz:ECS88_2461; -.
DR HOGENOM; CLU_068683_1_1_6; -.
DR Proteomes; UP000000747; Chromosome.
DR GO; GO:0030428; C:cell septum; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0042834; F:peptidoglycan binding; IEA:InterPro.
DR GO; GO:0032506; P:cytokinetic process; IEA:InterPro.
DR Gene3D; 3.30.70.1070; Sporulation related repeat; 1.
DR HAMAP; MF_02022; DedD; 1.
DR InterPro; IPR032898; DedD.
DR InterPro; IPR007730; SPOR-like_dom.
DR InterPro; IPR036680; SPOR-like_sf.
DR PANTHER; PTHR38687:SF1; CELL DIVISION PROTEIN DEDD; 1.
DR PANTHER; PTHR38687; CELL DIVISION PROTEIN DEDD-RELATED; 1.
DR Pfam; PF05036; SPOR; 1.
DR SUPFAM; SSF110997; Sporulation related repeat; 1.
DR PROSITE; PS51724; SPOR; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|HAMAP-Rule:MF_02022};
KW Cell division {ECO:0000256|HAMAP-Rule:MF_02022};
KW Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_02022};
KW Cell membrane {ECO:0000256|HAMAP-Rule:MF_02022};
KW Membrane {ECO:0000256|HAMAP-Rule:MF_02022};
KW Reference proteome {ECO:0000313|Proteomes:UP000000747};
KW Transmembrane {ECO:0000256|HAMAP-Rule:MF_02022};
KW Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_02022}.
FT TRANSMEM 9..27
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_02022"
FT DOMAIN 138..217
FT /note="SPOR"
FT /evidence="ECO:0000259|PROSITE:PS51724"
FT REGION 46..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 97..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..128
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 220 AA; 22967 MW; E55229D29C277BF2 CRC64;
MASKFQNRLV GTIVLVALGV IVLPGLLDGQ KKHYQDEFAA IPLVPKAGDR DEPDMMPAAT
QALPTQPPEG AAEEVRAGDA AAPSLDPATI AANNTEFEPE PAPVVPPKPK PVEPPKPKVE
APPAPKPEPK PVVEEKAAPT GKAYVVQLGA LKNADKVNEI VGKLRGAGYR VYTSPSTPVQ
GKITRILVGP DASKDKLKGS LGELKQLSGL SGVVMGYTPN
//
