ID   B7MN52_ECO45            Unreviewed;       410 AA.
AC   B7MN52;
DT   24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   24-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   SubName: Full=Immunoglobulin-binding regulator {ECO:0000313|EMBL:CAR04522.1};
GN   Name=ibrA {ECO:0000313|EMBL:CAR04522.1};
GN   OrderedLocusNames=ECS88_3288 {ECO:0000313|EMBL:CAR04522.1};
OS   Escherichia coli O45:K1 (strain S88 / ExPEC).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585035 {ECO:0000313|EMBL:CAR04522.1, ECO:0000313|Proteomes:UP000000747};
RN   [1] {ECO:0000313|Proteomes:UP000000747}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S88 / ExPEC {ECO:0000313|Proteomes:UP000000747};
RX   PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA   Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA   Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H.,
RA   Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.,
RA   Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C.,
RA   Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S.,
RA   Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J.,
RA   Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT   "Organised genome dynamics in the Escherichia coli species results in
RT   highly diverse adaptive paths.";
RL   PLoS Genet. 5:E1000344-E1000344(2009).
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DR   EMBL; CU928161; CAR04522.1; -; Genomic_DNA.
DR   RefSeq; WP_000999383.1; NC_011742.1.
DR   AlphaFoldDB; B7MN52; -.
DR   KEGG; ecz:ECS88_3288; -.
DR   HOGENOM; CLU_036373_0_0_6; -.
DR   Proteomes; UP000000747; Chromosome.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd01713; PAPS_reductase; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   InterPro; IPR021845; DUF3440.
DR   InterPro; IPR002500; PAPS_reduct.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR30083:SF0; 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SULFOTRANSFERASE (PAPS REDUCTASE)_FAD SYNTHETASE-RELATED; 1.
DR   PANTHER; PTHR30083; UNCHARACTERIZED; 1.
DR   Pfam; PF11922; DUF3440; 2.
DR   Pfam; PF01507; PAPS_reduct; 2.
DR   SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000747}.
FT   DOMAIN          34..89
FT                   /note="Phosphoadenosine phosphosulphate reductase"
FT                   /evidence="ECO:0000259|Pfam:PF01507"
FT   DOMAIN          165..240
FT                   /note="Phosphoadenosine phosphosulphate reductase"
FT                   /evidence="ECO:0000259|Pfam:PF01507"
SQ   SEQUENCE   410 AA;  48831 MW;  577AAD787B92DB09 CRC64;
     MNDNLLTEKV LTGENVLRAA IARIEWIFET FPSVCLSFSG GKDSTVLFHL LADVARRKKR
     RFSVLFIDWE AQYQCTIEHI QKMREMYHDV TETFYWVALP LTTVNGVSQF QPEWICWEPG
     VTWVRQPPEE AITDMTYFPF YRYAMTFEEF VPAFSSWFAD NKCGVAVLTG VRADESLNRF
     MGLVSQRKLR YADDKPWTTA SPEGFYYTMY PLYDWKTRDI WIYHTRTRAI YNPLYDLMYR
     AGVPLRNMRV CEPFGPEQRK GLWLYHVLEP DTWARMCERV SGAASGALYA NESGAYFALR
     KRISKPAHHT WRSYAMFLLD VMPERTAEHY RNKIAVYLRW YQTRGFPDDI PDEQENDLGC
     RDIPSWRRIC KTLIKNDFWC RTLSFSPNKP RHYERYLQRM KERRNEWGIL
//