ID   B7N5L2_ECOLU            Unreviewed;       402 AA.
AC   B7N5L2;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 61.
DE   SubName: Full=Transposase {ECO:0000313|EMBL:CAR13771.1};
GN   Name=ydcM {ECO:0000313|EMBL:CAR13771.1};
GN   OrderedLocusNames=ECUMN_2588 {ECO:0000313|EMBL:CAR13771.1};
OS   Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585056 {ECO:0000313|EMBL:CAR13771.1, ECO:0000313|Proteomes:UP000007097};
RN   [1] {ECO:0000313|Proteomes:UP000007097}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UMN026 / ExPEC {ECO:0000313|Proteomes:UP000007097};
RX   PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA   Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA   Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H.,
RA   Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.,
RA   Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C.,
RA   Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S.,
RA   Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J.,
RA   Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT   "Organised genome dynamics in the Escherichia coli species results in
RT   highly diverse adaptive paths.";
RL   PLoS Genet. 5:E1000344-E1000344(2009).
CC   -!- SIMILARITY: In the C-terminal section; belongs to the transposase 35
CC       family. {ECO:0000256|ARBA:ARBA00008761}.
CC   -!- SIMILARITY: In the N-terminal section; belongs to the transposase 2
CC       family. {ECO:0000256|ARBA:ARBA00011044}.
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DR   EMBL; CU928163; CAR13771.1; -; Genomic_DNA.
DR   RefSeq; WP_001310055.1; NC_011751.1.
DR   RefSeq; YP_002413299.1; NC_011751.1.
DR   AlphaFoldDB; B7N5L2; -.
DR   SMR; B7N5L2; -.
DR   STRING; 585056.ECUMN_2588; -.
DR   KEGG; eum:ECUMN_2588; -.
DR   PATRIC; fig|585056.7.peg.2768; -.
DR   HOGENOM; CLU_032903_0_4_6; -.
DR   Proteomes; UP000007097; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0032196; P:transposition; IEA:UniProtKB-KW.
DR   InterPro; IPR010095; Cas12f1-like_TNB.
DR   InterPro; IPR001959; Transposase.
DR   InterPro; IPR021027; Transposase_put_HTH.
DR   NCBIfam; NF040570; guided_TnpB; 1.
DR   NCBIfam; TIGR01766; IS200/IS605 family accessory protein TnpB-like domain; 1.
DR   PANTHER; PTHR30405:SF20; RNA-GUIDED DNA ENDONUCLEASE INSQ-RELATED; 1.
DR   PANTHER; PTHR30405; TRANSPOSASE; 1.
DR   Pfam; PF12323; HTH_OrfB_IS605; 1.
DR   Pfam; PF01385; OrfB_IS605; 1.
DR   Pfam; PF07282; OrfB_Zn_ribbon; 1.
PE   3: Inferred from homology;
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Transposition {ECO:0000256|ARBA:ARBA00022578};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          1..48
FT                   /note="Transposase putative helix-turn-helix"
FT                   /evidence="ECO:0000259|Pfam:PF12323"
FT   DOMAIN          162..277
FT                   /note="Probable transposase IS891/IS1136/IS1341"
FT                   /evidence="ECO:0000259|Pfam:PF01385"
FT   DOMAIN          304..372
FT                   /note="Cas12f1-like TNB"
FT                   /evidence="ECO:0000259|Pfam:PF07282"
SQ   SEQUENCE   402 AA;  45713 MW;  688AE63675F91F04 CRC64;
     MKRLQAFKFQ LRPGGQQECE MRRFAGACRF VFNRALALQN ENHEAGNKYI PYGKMASWLV
     EWKNATETQW LKDSPSQPLQ QSLKDLERAY KNFFQNRAAF PRFKKRGQND AFRYPQGVKL
     DQENSRIFLP KLGWMRYRNS RQVTGVVKNV TVSQSCGKWY ISIQTESEVS TPVHPSASMV
     GLDAGVAKLA TLSDGTVFEP VNSFQKNQKK LARLQRQLSR RVKFSNNWQK QKRKIQRLHS
     RIANIRRDYL HKVTTTVSKN HAMIVIEDLK VSNMSKSAAG TLSQPGRNVR AKSGLNRSIL
     DQGWYEMRRQ LEYKQLWSGG QLLAVPPAYT SQRCACCGHT AKENRLSQSQ FRCQVCGYTA
     NADVNGARNI LAAGHAVLAC GEMVQSGRSL KQEPTEMIQA TA
//